catalog number :
MBS628462
products full name :
SERPINA4, CT (Kallistatin, Kallikrein Inhibitor, Peptidase Inhibitor 4, Serpin A4, PI-4, Serpin A4, KST, PI4)
products short name :
SERPINA4
products name syn :
Anti -SERPINA4, CT (Kallistatin, Kallikrein Inhibitor, Peptidase Inhibitor 4, Serpin A4, PI-4, Serpin A4, KST, PI4)
other names :
Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4; Kallistatin; kallistatin; serpin A4; kallikrein inhibitor; peptidase inhibitor 4; protease inhibitor 4 (kallistatin); serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4; Kallikrein inhibitor; Peptidase inhibitor 4; PI-4; Serpin A4
other gene names :
SERPINA4; SERPINA4; KAL; KST; PI4; KLST; PI-4; kallistatin; KST; PI4
uniprot entry name :
KAIN_HUMAN
specificity :
Recognizes human SERPINA4 at ~48kD.
purity :
Purified. Purified by ammonium sulfate precipitation.
form :
Supplied as a liquid in PBS, 0.09% sodium azide.
storage stability :
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
tested application :
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
app notes :
Suitable for use in ELISA, Flow Cytometry, Immunohistochemistry and Western Blot. Dilution: ELISA: 1:1000. Flow Cytometry: 1:10-1:50. Immunohistochemistry: 1:50-1:100. Western Blot: 1:50-1:100
other info1 :
Immunogen: Synthetic peptide corresponding to region beween aa298-328 from the C-terminal region of human SERPINA4, conjugated to KLH.
products categories :
Antibodies; Abs to Protease Inhibitors
products description :
SERPINA4 inhibits human amidolytic and kininogenase activities of tissue kallikrein. The inhibition is achieved by formation of an equimolar, heat- and SDS-stable complex between the inhibitor and the enzyme, and generation of a small C-terminal fragment of the inhibitor due to cleavage at the reactive site by tissue kallikrein.
ncbi mol weight :
48,542 Da
uniprot summary :
SERPINA4: Inhibits human amidolytic and kininogenase activities of tissue kallikrein. Inhibition is achieved by formation of an equimolar, heat- and SDS-stable complex between the inhibitor and the enzyme, and generation of a small C-terminal fragment of the inhibitor due to cleavage at the reactive site by tissue kallikrein. Belongs to the serpin family. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 14q32.13. Cellular Component: extracellular space. Molecular Function: serine-type endopeptidase inhibitor activity