catalog number :
MBS626800
products full name :
MRII, NT (Anti-Muellerian Hormone Type II Receptor, Anti-Muellerian Hormone Type II Receptor, AMH Type II Receptor, MIS Type II Receptor, MISRII, AMHR2, AMHR)
products short name :
[MRII]
products name syn :
[Anti -MRII, NT (Anti-Muellerian Hormone Type II Receptor, Anti-Muellerian Hormone Type II Receptor, AMH Type II Receptor, MIS Type II Receptor, MISRII, AMHR2, AMHR)]
other names :
[monodehydroascorbate reductase II, MRII]
reactivity :
Human, Mouse
specificity :
Recognizes human AMHR2. Species Crossreactivity: mouse.
purity :
Affinity Purified. Purified by Protein G affinity chromatography.
form :
Supplied as a liquid in PBS, 0.09% sodium azide.
concentration :
1.9 mg/ml
storage stability :
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
tested application :
ELISA (EL/EIA), Western Blot (WB)
app notes :
Suitable for use in ELISA and Western Blot. Dilution: ELISA: 1:1,000. Western Blot: 1:100-1:500
image1 heading :
Western Blot (WB)
other info1 :
Immunogen: Synthetic peptide corresponding to a region between aa 20-50 from the N-terminal region of human AMHR2, conjugated to KLH.
other info2 :
Cellular Localization: Membrane; Single-pass type 1 membrane protein.
products categories :
Antibodies; Abs to Receptors
products description :
The AMH receptor (AMHR or AMHR2) is a serine/threonine kinase with a single transmembrane domain belonging to the family of type II receptors for TGF-beta-related proteins. Anti-Mullerian hormone (AMH) and its receptor are involved in the regression of Mullerian ducts in male fetuses. Male sex differentiation is mediated by 2 discrete hormones produced by the fetal testis. Testosterone, produced by Leydig cells, virilizes the external genitalia and promotes prostatic growth; anti-Mullerian hormone (AMH) results in regression of Mullerian ducts which would otherwise differentiate into the uterus and fallopian tubes.
ncbi pathways :
Focal Adhesion Pathway (83067); Focal Adhesion Pathway (478); MAPK Signaling Pathway (83048); MAPK Signaling Pathway (456); Salmonella Infection Pathway (375172); Salmonella Infection Pathway (375149)