catalog number :
MBS625895
products full name :
Thyroid Stimulating Hormone, intact (TSHintact)
products short name :
[Thyroid Stimulating Hormone, intact]
products name syn :
[Anti -Thyroid Stimulating Hormone, intact (TSHintact)]
specificity :
Recognizes human TSH, a+b subunits. May crossreact with the alpha subunits of LH, FSH and hCG.
purity :
Affinity Purified. Purified by immunoaffinity chromatography.
form :
Supplied as a liquid in PBS, pH 7.2, 0.05% sodium azide.
concentration :
5.16 mg/ml (E1%, 280nm= 13.0)
storage stability :
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
tested application :
ELISA (EL/EIA)
app notes :
Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry, FACS, Immunoflourescence. Other applications not tested.
other info1 :
Immunogen: Human TSH from pituitary glands
products categories :
Antibodies; Abs to Hormones, Steroids
products description :
Thyroid-stimulating hormone (TSH or thyrotropin), produced in human pituitary glands, has a molecular mass of 25kD. An Important indicator of thyroid function, TSH is used to monitor thyroid associated diseases. Thyroid-stimulating hormone is a hormone synthesized and secreted by thyrotrope cells in the anterior pituitary gland which regulates the endocrine function of the thyroid gland. TSH stimulates the thyroid gland to secrete the hormones thyroxine (T4) and triiodothyronine (T3). TSH production is controlled by a Thyrotropin Releasing Hormone (TRH), which is manufactured in the hypothalamus and transported to the anterior pituitary gland, where it increases TSH production and release. Somatostatin is also produced by the hypothalamus, and has an opposite effect on the pituitary production of TSH, decreasing or inhibiting its release.