catalog number :
MBS623957
products full name :
Neuromedin U-8 (NmU-8, NMU)
products short name :
Neuromedin U-8
products name syn :
Anti -Neuromedin U-8 (NmU-8, NMU)
other names :
Neuromedin-U-25
reactivity :
Chicken, Rat
specificity :
Recognizes Neuromedin U-8. Species Crossreactivity: chicken, rat
form :
Supplied as a lyophilized powder. Reconstitute in 50-100ul sterile ddH2O. Dilute further in 0.1M PBS, 1% BSA, 0.1% sodium azide.
storage stability :
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
tested application :
Immunohistochemistry (IHC)
app notes :
Suitable for use in Immunohistochemistry. Dilution: Immunohistochemistry (Frozen): 1:1000-1:1500 using FITC. Incubate overnight at 4 C.
other info1 :
Immunogen: Synthetic sequence from porcine Neuromedin U-8 conjugated to BSA.
other info2 :
Positive Control: Frozen sections of chicken small intestine.
products categories :
Antibodies; Abs to Neuroscience
products description :
Neuromedin U (or NmU) is a neuropeptide found in the brain of humans and other mammals, which has a number of diverse functions including contraction of smooth muscle, regulation of blood pressure, pain perception, appetite, bone growth, and hormone release. It was first isolated from the spinal cord in 1985, and named after its ability to cause smooth muscle contraction in the uterus. Neuromedin U is a highly conserved neuropetide present in many species, existing as multiple isoforms. For example, in humans it is a 25 amino acid peptide (U-25) in rats it is 23aa long (U-23) and it has been found to be as low as 8aa long in some mammals. NMU-8 is identical to the C-terminus of NMU-25, thus is the most highly conserved region of the entire peptide. The relative contribution of the different isoforms to the biological function of neuromedin U is generally not well understood. Neuromedin U, like many neuroactive peptides, is amidated at the C-terminus, and all isoforms have identical C-terminal heptapeptides.