catalog number :
MBS622772
products full name :
CD44v3 - v10 (CD44 Antigen, CD44 Molecule, Heparan Sulfate Proteoglycan, MUTCH 1, Phagocytic Glycoprotein I)
products short name :
CD44v3- v10
products name syn :
Anti -CD44v3 - v10 (CD44 Antigen, CD44 Molecule, Heparan Sulfate Proteoglycan, MUTCH 1, Phagocytic Glycoprotein I)
specificity :
Recognizes epitopes encoded by exons v3-v10 on the varient portion of human CD44.
purity :
Affinity Purified. Purified by affinity chromatography.
form :
Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide.
storage stability :
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
tested application :
Immunohistochemistry (IHC)
app notes :
Suitable for use in Immunohistochemistry. Dilution: Immunohistochemistry (Frozen): 50ug/ml. Immunohistochemistry (Paraffin): 20ug/ml. Requires antigen retrieval using heat treatment prior to staining of paraffin sections. Use sodium citrate buffer pH 6.0.
other info1 :
Immunogen: Recombinant human CD44v3-v10
other info2 :
Positive Control: Breast carcinoma and colon adenocarcinoma
products categories :
Antibodies; Abs to CD Markers
products description :
CD44 is a ubiquitously expressed type 1 transmembrane glycoprotein and proteoglycan, otherwise known as phagocytic glycoprotein 1 (pgp 1), which acts as a receptor for the major extracellular matrix component hyaluronate, and also binds other ligands including collagen and matrix metalloproteinases (MMPs). CD44 is known to play a role in cell-cell interactions, cell adhesion, the activation and homing of lymphocytes, cell migration, hematopoiesis and metastasis, and exists as a number of isoforms generated by the alternative RNA splicing of at least 10 variant exons (CD44v).