catalog number :
MBS622742
products full name :
Chorionic Gonadotropin, Equine (CG)
products short name :
[Chorionic Gonadotropin, Equine]
products name syn :
[Anti -Chorionic Gonadotropin, Equine (CG)]
other names :
[cytochrome P450 19A1; Cytochrome P450 19A1; cytochrome P450 19A1; CYPXIX; aromatase; estrogen synthase; cytochrome P-450AROM; cytochrome P450 17-alpha; Aromatase; CYPXIX; Cytochrome P-450AROM; Cytochrome P450 17-alpha; Estrogen synthase]
other gene names :
[CYP19A1; CYP19A1; P450AROM; CYP19]
uniprot entry name :
CP19A_HORSE
specificity :
Recognizes equine Chorionic Gonadotropin
form :
Supplied as a lyophilized powder. Reconstitute with 20ul of sterile ddH2O.
storage stability :
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
tested application :
Western Blot (WB), Radioimmunoassay (RIA).
app notes :
Suitable for use in RIA and Western Blot. Other applications not tested. Recommended Dilutions: Optimal dilutions to be determined by the researcher.
other info1 :
Immunogen: Purified equine Chorionic Gonadotropin
products categories :
Antibodies; Abs to Hormones, Steroids
products description :
Equine chorionic gonadotropin (eCG) is a gonadotropic hormone produced in the chorion of pregnant mares. Most commonly called pregnant mare's serum gonadotropin (PMSG) in the past, the hormone is commonly used in concert with progestogen to induce ovulation in livestock prior to artificial insemination.
ncbi acc num :
NP_001075274.1
ncbi gb acc num :
NM_001081805.1
ncbi mol weight :
57,825 Da
ncbi pathways :
C19/C18-Steroid Hormone Biosynthesis, Pregnenolone = Androstenedione = Estrone Pathway (403683); C19/C18-Steroid Hormone Biosynthesis, Pregnenolone = Androstenedione = Estrone Pathway (468268); Ovarian Steroidogenesis Pathway (790545); Ovarian Steroidogenesis Pathway (795173); Steroid Hormone Biosynthesis Pathway (94721); Steroid Hormone Biosynthesis Pathway (301)
uniprot summary :
Function: Catalyzes the formation of aromatic C18 estrogens from C19 androgens. Final rate-limiting step. Catalytic activity: RH + reduced flavoprotein + O2 = ROH + oxidized flavoprotein + H2O. Cofactor: Heme group . By similarity. Subcellular location: Endoplasmic reticulum membrane; Peripheral membrane protein . By similarity. Tissue specificity: Expressed in placenta. Highly expressed in follicles (0 hour:hCG), followed by a drop (12-24 hour:hCG) and by an increase (30-39 hour:hCG). Highly expressed in corpora lutea. Also expressed in granulosa cell layer. Not expressed in theca interna. Domain: Contains a I helix thought to serve as the substrate-binding pocket. Sequence similarities: Belongs to the cytochrome P450 family. Caution: Clone A1 form may be a splice variant or an artifact.