product summary
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company name :
MyBioSource
product type :
antibody
product name :
LINE-1 (L1, Long Interspersed Element, Retrotransposon ORF2)
catalog :
MBS622333
quantity :
0.1 mg
price :
755 USD
clonality :
polyclonal
host :
chicken
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, enzyme immunoassay
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS622333 image 1
Western Blot using MBS622333 shows detection of induced bacterially expressed human ORF2 (left lane). No specific band staining is seen in the uninduced lane (right lane). The lower molecular weight bands represent non-specific staining. The band at ~70kD corresponds to a human L1/ORF2 EN domain fusion protein (arrowhead).
product information
catalog number :
MBS622333
products type :
Antibody
products full name :
LINE-1 (L1, Long Interspersed Element, Retrotransposon ORF2)
products short name :
[LINE-1]
products name syn :
[Anti -LINE-1 (L1, Long Interspersed Element, Retrotransposon ORF2)]
other names :
[LINE-1 type transposase domain-containing protein 1; LINE-1 type transposase domain-containing protein 1; LINE-1 type transposase domain-containing protein 1; ES cell-associated protein 11; LINE-1 type transposase domain containing 1; ES cell-associated protein 11]
other gene names :
[L1TD1; L1TD1; ECAT11; RP5-1155K23.3; ECAT11]
uniprot entry name :
LITD1_HUMAN
clonality :
Polyclonal
isotype :
IgY
host :
Chicken
reactivity :
Human
specificity :
Recognizes human LINE-1 at ~149kD.
purity :
Purified. Purified by selective precipitation and salt fractionation followed by extensive dialysis.
form :
Supplied as a liquid in PBS, pH 7.2, 0.01% sodium azide.
concentration :
1mg/ml
storage stability :
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
tested application :
ELISA (EL/EIA), Western Blot (WB)
app notes :
Suitable for use in ELISA and Western Blot. Dilution: ELISA: 1:10,000. Western Blot: 1:2000-1:10,000
image1 heading :
Western Blot (WB)
other info1 :
Immunogen: Synthetic peptides corresponding to regions within the endonuclease domain of human LINE-1, conjugated to KLH. Species Sequence Homology: Chimpanzee; 100%, macaque, fruit fly, bovine, canine, opossum, rat; 69-88%
products categories :
Antibodies; Abs to Proteins
products description :
The L1 (LINE-1), or Long INterspersed Element, retrotransposon ORF2 is the most common open reading frame in the human genome, present in various forms in many thousands of copies. This large family of proteins includes magnesium dependent endonucleases and a large number of phosphatases involved in intracellular signaling. Both intact ORF1 and ORF2 are absolutely required for autonomous retro-transposition. ORF2 encodes an endonuclease, reverse transcriptase, and zinc knuckle domains. The expression of ORF2 appears to be tightly regulated except in germ line tissues, embryonic tissues, and certain cancers including teratomas, testicular cancers, and leukemias. This antibody is intended for use in studying control of L1 retrotransposons.
ncbi gi num :
258679511
ncbi acc num :
NP_001158307.1
ncbi gb acc num :
NM_001164835.1
uniprot acc num :
Q5T7N2
ncbi mol weight :
~149kD
uniprot summary :
L1TD1: Belongs to the transposase 22 family. Chromosomal Location of Human Ortholog: 1p31.3
size1 :
0.1 mg
price1 :
755 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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