catalog number :
MBS621803
products full name :
Elastin, alpha (alpha Elastin, Elastin Isoform a, ELN, FLJ38671, FLJ43523, Supravalvular Aortic Stenosis, SVAS, WBS, WS)
products short name :
[Elastin, alpha]
products name syn :
[Anti -Elastin, alpha (alpha Elastin, Elastin Isoform a, ELN, FLJ38671, FLJ43523, Supravalvular Aortic Stenosis, SVAS, WBS, WS)]
other names :
[elastin microfibril interfase located protein]
reactivity :
Bovine, Human
specificity :
Recognizes human alpha ELASTIN. Species Crossreactivity: bovine and tree shrew.
purity :
Affinity Purified. Purified by Protein G affinity chromatography.
form :
Supplied as a liquid in PBS, 0.09% sodium azide.
storage stability :
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
tested application :
ELISA (EL/EIA), Immunohistochemistry (IHC)
app notes :
ELISA: 1:8000. The 50% OD was observed using 1ug of native antigen/well. Under the same conditions, the end-point was observed at 1:200,000. Immunohistochemistry (Paraffin): Fixation with 10% formalin is recommeded. Brief digestion with hyaluronidase or trypsin aids antigen retrieval. Optimal dilutions to be determined by the researcher.
other info1 :
Immunogen: Human alpha elastin
products categories :
Antibodies; Abs to Elastin
products description :
Elastin is a major structural protein expressed withing the outer myometrial smooth muscle and throughout the arteriolar tree of uterus. It is also expressed in the alrge arteries, lung and skin.
ncbi acc num :
AAF25006.1
uniprot summary :
EMILIN1: May be responsible for anchoring smooth muscle cells to elastic fibers, and may be involved not only in the formation of the elastic fiber, but also in the processes that regulate vessel assembly. Has cell adhesive capacity. Protein type: Cell adhesion; Extracellular matrix; Secreted, signal peptide; Secreted; Motility/polarity/chemotaxis. Chromosomal Location of Human Ortholog: 2p23.3-p23.2. Cellular Component: extracellular matrix; proteinaceous extracellular matrix; collagen; extracellular region. Molecular Function: identical protein binding; protein binding; extracellular matrix constituent conferring elasticity. Biological Process: extracellular matrix organization and biogenesis; cell adhesion