Estrogen, Total | MyBioSource MBS620830 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Estrogen, Total

catalog :

MBS620830

quantity :

1000 Tests

price :

370 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

rat

application :

ELISA, radioimmunoassay, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS620830

products type :

Antibody

products full name :

Estrogen, Total

products short name :

Estrogen, Total

products name syn :

Anti -Estrogen, Total

other names :

estrogen receptor beta; Estrogen receptor beta; estrogen receptor beta; estrogen receptor 2 beta; nuclear receptor subfamily 3 group A member 2; estrogen receptor 2 (ER beta); Nuclear receptor subfamily 3 group A member 2

other gene names :

Esr2; Esr2; Erb2; ERbeta; ER-beta; Erbeta; Nr3a2; ER-beta

uniprot entry name :

ESR2_RAT

clonality :

Polyclonal

isotype :

IgG

host :

Rabbit

specificity :

Recognizes total Estrogen: 100%.

purity :

Serum. Serum

form :

Supplied as a liquid. No preservatives added

storage stability :

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

tested application :

ELISA (EL/EIA), Radioimmunoassay (RIA)

app notes :

Suitable for use in RIA and ELISA. Dilution: RIA: 33,000test/ml

other info1 :

Immunogen: Estriol (BSA)

products categories :

Antibodies; Abs to Hormones, Steroids

ncbi gi num :

3077649

ncbi acc num :

CAA05631.1

uniprot acc num :

Q62986

ncbi mol weight :

59,152 Da

ncbi pathways :

Androgen Receptor Signaling Pathway (198529); Estrogen Signaling Pathway (799190); Estrogen Signaling Pathway (799197); Gene Expression Pathway (828948); Generic Transcription Pathway (828949); Nuclear Receptor Transcription Pathway (828951); Nuclear Receptors Pathway (198498); Ovarian Infertility Genes Pathway (198450); Prolactin Signaling Pathway (814205); Prolactin Signaling Pathway (814248)

ncbi summary :

binds estrogen and mediates transcriptional activation [RGD, Feb 2006]

uniprot summary :

ER-beta: a nuclear hormone receptor and transcription factor. Binds and activated by estrogen. Regulates gene expression and affects cellular proliferation and differentiation in target tissues. Binds estrogens with an affinity similar to that of ER-alpha, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. Eight alternatively-spliced isoforms have been described. Isoform beta-cx lacks ligand binding ability and has no or only very low ERE binding activity resulting in the loss of ligand-dependent transactivation ability. Protein type: Nuclear receptor; DNA-binding. Cellular Component: neuron projection; cell soma; mitochondrion; perinuclear region of cytoplasm; cytoplasm; plasma membrane; perikaryon; nucleus; cilium. Molecular Function: peroxisome proliferator activated receptor binding; ligand-dependent nuclear receptor activity; estrogen receptor activity; hormone binding; zinc ion binding; estrogen response element binding; drug binding; steroid binding; protein binding; enzyme binding; DNA binding; sequence-specific DNA binding; steroid hormone receptor activity; transcription factor activity. Biological Process: prostate gland development; hypothalamus development; behavioral fear response; estrogen receptor signaling pathway; negative regulation of smooth muscle cell proliferation; positive regulation of apoptosis; induction of apoptosis by hormones; positive regulation of transcription, DNA-dependent; response to hormone stimulus; neuron migration; amygdala development; negative regulation of transcription from RNA polymerase II promoter; response to insecticide; uterus development; response to organic cyclic substance; response to estradiol stimulus; negative regulation of cell proliferation; learning and/or memory; ovarian follicle development; regulation of transcription, DNA-dependent; positive regulation of epidermal growth factor receptor signaling pathway; regulation of neuron apoptosis; cerebellum development; female gonad development; negative regulation of epithelial cell proliferation; response to nutrient levels; response to drug; steroid hormone receptor signaling pathway; transcription, DNA-dependent; male gonad development; vagina development; Sertoli cell proliferation; response to testosterone stimulus; Sertoli cell development; regulation of cell proliferation; response to genistein; response to ethanol; response to estrogen stimulus; positive regulation of transcription factor activity; steroid hormone mediated signaling; positive regulation of transcription from RNA polymerase II promoter; response to activity; brain development; negative regulation of behavior; response to water deprivation

size1 :

1000 Tests

price1 :

370 USD

more info or order :

MyBioSource product webpage