antibody

Goat anti-ENOX2 (APK1, Ecto-NOX Disulfide-thiol Exchanger 2, RP5-875H3.1, COVA1, tNOX, Acytosolic Ovarian Carcinoma Antigen 1)

MBS620010

0.1 mg

415 USD

polyclonal

goat

nonconjugated

western blot, ELISA, enzyme immunoassay, other

Antibody

Goat anti-ENOX2 (APK1, Ecto-NOX Disulfide-thiol Exchanger 2, RP5-875H3.1, COVA1, tNOX, Acytosolic Ovarian Carcinoma Antigen 1)

ENOX2

Anti -ENOX2 (APK1, Ecto-NOX Disulfide-thiol Exchanger 2, RP5-875H3.1, COVA1, tNOX, Acytosolic Ovarian Carcinoma Antigen 1)

ecto-NOX disulfide-thiol exchanger 2 isoform a; Ecto-NOX disulfide-thiol exchanger 2; ecto-NOX disulfide-thiol exchanger 2; APK1 antigen; OTTHUMP00000024021; OTTHUMP00000024022; cytosolic ovarian carcinoma antigen 1; tumor-associated hydroquinone oxidase; ecto-NOX disulfide-thiol exchanger 2; APK1 antigen; Cytosolic ovarian carcinoma antigen 1; Tumor-associated hydroquinone oxidase

ENOX2; ENOX2; APK1; tNOX; COVA1; COVA1

ENOX2_HUMAN

Polyclonal

IgG

Goat

Recognizes ENOX2.

Affinity Purified. Purified by affinity chromatography

Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide

0.5mg/ml

May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

ELISA (EL/EIA) and Western Blot. Other applications not tested.

Recommended Dilution: Peptide ELISA: 1:64,000. Western Blot: 0.03ug/ml. A band is detected at ~60kD and 37kD in Human Heart lysates.

Immunogen: Synthetic peptide corresponding to C-EKLKDDKLQVEK, from ENOX2, at the internal region of the protein (NP_006366.2; NP_872114.1). Species sequence homology: canine

Accession Number: NP_006366.2. NP_872114.1

Antibodies; Abs to Cancer Markers

32528293

NP_006366.2

NM_006375.2

Q16206

The protein encoded by this gene is a growth-related cell surface protein. It was identifed because it reacts with the monoclonal antibody KI in cells, such as the ovarian carcinoma line OVCAR-3, also expressing the CAKI surface glycoprotein. The encoded protein has two enzymatic activities: catalysis of hydroquinone or NADH oxidation, and protein disulfide interchange. The two activities alternate with a period length of about 24 minutes. The encoded protein also displays prion-like properties. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

ENOX2: May be involved in cell growth. Probably acts as a terminal oxidase of plasma electron transport from cytosolic NAD(P)H via hydroquinones to acceptors at the cell surface. Hydroquinone oxidase activity alternates with a protein disulfide- thiol interchange/oxidoreductase activity which may control physical membrane displacements associated with vesicle budding or cell enlargement. The activities oscillate with a period length of 22 minutes and play a role in control of the ultradian cellular biological clock. Belongs to the ENOX family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: EC 1.-.-.-; Cell surface; Oxidoreductase; Cytoskeletal. Chromosomal Location of Human Ortholog: Xq25. Cellular Component: extracellular space; cytosol; external side of plasma membrane. Molecular Function: nucleic acid binding; nucleotide binding; protein disulfide oxidoreductase activity. Biological Process: regulation of growth; cell growth; ultradian rhythm

0.1 mg

415 USD