antibody

Epidermal Fatty Acid Binding Protein (EFABP, FABP5)

MBS619811

0.1 mg

475 USD

polyclonal

sheep

nonconjugated

human, cow

western blot, ELISA, enzyme immunoassay

Antibody

Epidermal Fatty Acid Binding Protein (EFABP, FABP5)

Epidermal Fatty Acid Binding Protein

Anti -Epidermal Fatty Acid Binding Protein (EFABP, FABP5)

epidermal fatty acid-binding protein; Fatty acid-binding protein, epidermal; fatty acid-binding protein, epidermal; E-FABP; fatty acid-binding protein 5; epidermal fatty acid-binding protein; epidermal-type fatty acid-binding protein; differentiation-associated lipid-binding protein LP2; Differentiation-associated lipid-binding protein LP2; Epidermal-type fatty acid-binding protein; E-FABP; Fatty acid-binding protein 5

FABP5; FABP5; MGC128055

FABP5_BOVIN

Polyclonal

IgG

Sheep

Human

Recognizes human FABP5.

Affinity Purified. Purified by Immunoaffinity chromatography.

Supplied as a lyophilized powder in PBS, pH 7.2. No preservative added. Reconstitute with 100ul sterile dH2O. Let the lyophilized pellet dissolve completely.

-20 degree C

ELISA (EL/EIA), Western Blot (WB)

Suitable for use in ELISA and Western Blot.

Immunogen: Recombinant human FABP5 expressed in E. coli

Antibodies; Abs to Fatty Acid Binding Protein

Human fatty acid binding protein EFABP is a 15kD member of the intracellular fatty acid binding protein (FABP) family, which is known for the ability to bind fatty acids and related compounds (bile acids or retinoids). in an internal cavity. The fatty acid binding proteins aP2 (fatty acid binding protein [FABP]-4) and mal1 (EFABP) are closely related and both are expressed in adipocytes. Absence of EFABP/mal1 resulted in increased systemic insulin sensitivity in two models of obesity and insulin resistance. Adipocytes isolated from mal1-deficient mice also exhibited enhanced insulin-stimulated glucose transport capacity. In contrast, mice expressing high levels of mal1 in adipose tissue display reduced systemic insulin sensitivity.

3088569

P55052

15,074 Da

PPAR Signaling Pathway (84281); PPAR Signaling Pathway (450)

Function: High specificity for fatty acids. Highest affinity for the unsaturated fatty acid palmitate (C16:0). May be involved in the uptake and transport of fatty acids essential for the nourishment of the surrounding cell types. It is a potential target for oxidative stress during cataract formation in lens. Subcellular location: Cytoplasm. Tissue specificity: Most abundant in lens and retina (found in the mueller cells), moderately abundant in heart and testis (found in the Sertoli cells), and present in very low amounts in lung. Domain: Forms a beta-barrel structure that accommodates hydrophobic ligands in its interior. Sequence similarities: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

0.1 mg

475 USD