ADMA (Asymmetric Dimethylarginine) | MyBioSource MBS619029 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

ADMA (Asymmetric Dimethylarginine)

catalog :

MBS619029

quantity :

0.01 mg

price :

380 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS619029

products type :

Antibody

products full name :

ADMA (Asymmetric Dimethylarginine)

products short name :

ADMA

products name syn :

Anti -ADMA (Asymmetric Dimethylarginine)

other names :

alanine--glyoxylate aminotransferase 2, mitochondrial; Alanine--glyoxylate aminotransferase 2, mitochondrial; alanine--glyoxylate aminotransferase 2, mitochondrial; beta-ALAAT II; beta-alanine-pyruvate aminotransferase; (R)-3-amino-2-methylpropionate--pyruvate transaminase; alanine--glyoxylate aminotransferase 2; (R)-3-amino-2-methylpropionate--pyruvate transaminase (EC:2.6.1.40); Beta-ALAAT II; Beta-alanine-pyruvate aminotransferase; D-AIBAT

other gene names :

AGXT2; AGXT2; AGT2; DAIBAT; AGT2; AGT 2

uniprot entry name :

AGT2_HUMAN

clonality :

Polyclonal

isotype :

IgG1

host :

Rabbit

reactivity :

Using conjugated ADMA-KLH, antibody specificity was performed with an ELISA test by competition experiences with the following compounds:. Compound: Cross-reactivity ration(a). ADMA-BSA: 1. SDMA-BSA: 1:>100. NDMA-BSA: 1:>100. L-Arginine-BSA: 1:>

specificity :

Recognizes ADMA.

purity :

Affinity Purified. Purified by Protein G affinity chromatography.

form :

Supplied as a lyophilized powder from 50mM Tris, pH 7.4. Reconstitute with sterile ddH2O to a concentration of 1mg/ml.

concentration :

1mg/ml

storage stability :

Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

tested application :

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

other info1 :

Immunogen: ADMA, conjugated to KLH.

other info2 :

Crossreactivity Notes: (a) ASMA-BSA concentration/unconjugated or conjugated amino acids concentration at half displacement BSA=Bovine Serum Albumin

products categories :

Antibodies; Abs to Amino Acids

products description :

Asymmetric dimethylarginine (ADMA) is a naturally occurring chemical found in blood plasma. It is a metabolic by-product of continual protein modification processes in the cytoplasm of all human cells. It is closely related to L-arginine, a conditionally-essential amino acid. ADMA interferes with L-arginine in the production of nitric oxide, a key chemical involved in normal endothelial function and, by extension, cardiovascular health.

ncbi gi num :

13994255

ncbi acc num :

NP_114106.1

ncbi gb acc num :

NM_031900.3

uniprot acc num :

Q9BYV1

ncbi mol weight :

57,156 Da

ncbi pathways :

Alanine, Aspartate And Glutamate Metabolism Pathway (101142); Alanine, Aspartate And Glutamate Metabolism Pathway (100063); Glycine, Serine And Threonine Metabolism Pathway (82949); Glycine, Serine And Threonine Metabolism Pathway (313); Glyoxylate Metabolism Pathway (160990); Metabolism Pathway (477135); Metabolism Of Amino Acids And Derivatives Pathway (106169); Metabolism Of Nucleotides Pathway (106263); Pyrimidine Catabolism Pathway (106288); Pyrimidine Metabolism Pathway (106281)

ncbi summary :

The protein encoded by this gene is a class III pyridoxal-phosphate-dependent mitochondrial aminotransferase. It catalyzes the conversion of glyoxylate to glycine using L-alanine as the amino donor. [provided by RefSeq, Dec 2008]

uniprot summary :

AGXT2: is a class III pyridoxal-phosphate-dependent mitochondrial aminotransferase. It catalyzes the conversion of glyoxylate to glycine using L-alanine as the amino donor. [provided by RefSeq, Dec 2008]. Protein type: EC 2.6.1.44; Transferase; Mitochondrial; Amino Acid Metabolism - alanine, aspartate and glutamate; EC 2.6.1.40. Chromosomal Location of Human Ortholog: 5p13. Cellular Component: mitochondrion; mitochondrial matrix. Molecular Function: beta-alanine-pyruvate transaminase activity; alanine-glyoxylate transaminase activity; (R)-3-amino-2-methylpropionate-pyruvate transaminase activity; pyridoxal phosphate binding. Biological Process: pyrimidine nucleoside catabolic process; positive regulation of nitric oxide biosynthetic process; glyoxylate catabolic process; pyrimidine base metabolic process; glyoxylate metabolic process; nucleobase, nucleoside and nucleotide metabolic process; glycine biosynthetic process, by transamination of glyoxylate; L-alanine catabolic process, by transamination

size1 :

0.01 mg

price1 :

380 USD

size2 :

0.1 mg

price2 :

815

more info or order :

MyBioSource product webpage