ACOX2 (Acyl-Coenzyme A Oxidase 2, Branched Chain, BCOX, BRCACOX, BRCOX, THCCox, Peroxisomal Branched Chain Acyl-CoA Oxidase, THCA-CoA Oxidase, Trihydroxycoprostanoyl-CoA Oxidase) | MyBioSource MBS617705 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

MyBioSource

product type :

antibody

product name :

ACOX2 (Acyl-Coenzyme A Oxidase 2, Branched Chain, BCOX, BRCACOX, BRCOX, THCCox, Peroxisomal Branched Chain Acyl-CoA Oxidase, THCA-CoA Oxidase, Trihydroxycoprostanoyl-CoA Oxidase)

catalog :

MBS617705

quantity :

0.1 mg

price :

610 USD

clonality :

polyclonal

host :

goat

reactivity :

human

application :

western blot, ELISA, enzyme immunoassay

product information

catalog number :

MBS617705

products type :

Antibody

products full name :

ACOX2 (Acyl-Coenzyme A Oxidase 2, Branched Chain, BCOX, BRCACOX, BRCOX, THCCox, Peroxisomal Branched Chain Acyl-CoA Oxidase, THCA-CoA Oxidase, Trihydroxycoprostanoyl-CoA Oxidase)

products short name :

ACOX2

products name syn :

Anti -ACOX2 (Acyl-Coenzyme A Oxidase 2, Branched Chain, BCOX, BRCACOX, BRCOX, THCCox, Peroxisomal Branched Chain Acyl-CoA Oxidase, THCA-CoA Oxidase, Trihydroxycoprostanoyl-CoA Oxidase)

other names :

peroxisomal acyl-coenzyme A oxidase 2; Peroxisomal acyl-coenzyme A oxidase 2; peroxisomal acyl-coenzyme A oxidase 2; THCA-CoA oxidase; OTTHUMP00000214196; OTTHUMP00000214197; trihydroxycoprostanoyl-CoA oxidase; acyl-Coenzyme A oxidase 2, branched chain; peroxisomal branched chain acyl-CoA oxidase; 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl-CoA oxidase; 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl-CoA 24-hydroxylase; acyl-CoA oxidase 2, branched chain; 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl-CoA 24-hydroxylase; 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl-CoA oxidase; Trihydroxycoprostanoyl-CoA oxidase

other gene names :

ACOX2; ACOX2; BCOX; BRCOX; THCCox; BRCACOX

uniprot entry name :

ACOX2_HUMAN

clonality :

Polyclonal

isotype :

IgG

host :

Host: Goat; Source: Human

reactivity :

Human

purity :

Affinity Purified. Purified by immunoaffinity chromatography.

form :

Supplied as a liquid in Tris-saline, pH7.2, 0.5% BSA.

storage stability :

May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

tested application :

ELISA (EL/EIA), Western Blot (WB)

app notes :

Suitable for use in ELISA and Western Blot. Dilution: ELISA: 1:4,000. Western Blot: 0.5-1.5ug/ml. ~ 75kD band observed in Human Liver lysates (calculated MW of 76.8kD according to NP_003491.1).

other info1 :

Immunogen: Synthetic peptide, C-QWAQKSPTNTQENP, representing the internal region (near the C Terminus) of the human sequence according to NP_003491.1. Homology: Human Epitope: QWAQKSPTNTQENP

products categories :

Antibodies; Abs to Enzymes, Oxidase

products description :

The product of this gene belongs to the acyl-CoA oxidases family. It encodes the branched-chain acyl-CoA oxidase which is involved in the degradation of long branched fatty acids and bile acid intermediates in peroxisomes. Deficiency of this enzyme results in the accumulation of branched fatty acids and bile acid intermediates, and may lead to Zellweger syndrome, severe mental retardation and death in children.

ncbi gi num :

4501869

ncbi acc num :

NP_003491.1

ncbi gb acc num :

NM_003500.3

uniprot acc num :

Q99424

ncbi mol weight :

76,827 Da

ncbi pathways :

Beta-oxidation Of Pristanoyl-CoA Pathway 106138!!Bile Acid And Bile Salt Metabolism Pathway 106144!!Metabolic Pathways 132956!!Metabolism Of Lipids And Lipoproteins Pathway 160976!!PPAR Signaling Pathway 83042!!PPAR Signaling Pathway 450!!Peroxisomal Lipid Metabolism Pathway 106136!!Peroxisome Pathway 131226!!Peroxisome Pathway 131126!!Primary Bile Acid Biosynthesis Pathway 82938

ncbi summary :

The product of this gene belongs to the acyl-CoA oxidase family. It encodes the branched-chain acyl-CoA oxidase which is involved in the degradation of long branched fatty acids and bile acid intermediates in peroxisomes. Deficiency of this enzyme results in the accumulation of branched fatty acids and bile acid intermediates, and may lead to Zellweger syndrome, severe mental retardation, and death in children. [provided by RefSeq]

uniprot summary :

Function: Oxidizes the CoA esters of the bile acid intermediates di- and tri-hydroxycholestanoic acids. Catalytic activity: (25R)-3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestan-26-oyl-CoA + H2O + acceptor = (24R,25R)-3-alpha,7-alpha,12-alpha,24-tetrahydroxy-5-beta-cholestan-26-oyl-CoA + reduced acceptor. Cofactor: FAD. Subunit structure: Heterodimer. Subcellular location: Peroxisome. Tissue specificity: Present in all tissues tested: heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Most abundant in heart, liver and kidney. Sequence similarities: Belongs to the acyl-CoA oxidase family.

size :

0.1 mg

price :

610 USD