catalog number :
MBS617582
products full name :
Myostatin Propeptide
products short name :
[Myostatin Propeptide]
products name syn :
[Anti -Myostatin Propeptide]
other names :
[myostatin]
sequence :
MGNENSEQKE NVEKEGLCNA CTWRQNTKSS RIEAIKIQIL SKLRLETAPN ISKDVIRQLL PKAPPLRELI DQYDVQRDDS SDGSLEDDDY HATTETIITM PTESDFLMQV DGKPKCCFFK FSSKIQYNKV VKAQLWIYLR PVETPTTVFV QILRLIKPMK DGTRYTGIRS LKLDMNPGTG IWQSIDVKTV LQNWLKQPES NLGIEIKALD ENGHDLAVTF PGPGEDGLNP FLEVKVTDTP KRSRRKLN
specificity :
Recognizes human Myostatin Propeptide.
purity :
Affinity Purified. Purified by immunoaffinity chromatography.
form :
Supplied as a lyophilized powder from PBS, pH 7.2. Reconstitute with 50ul sterile ddH2O.
storage stability :
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
tested application :
ELISA (EL/EIA), Western Blot (WB)
app notes :
Suitable for use in ELISA and Western Blot. Dilution: ELISA: Indirect
other info1 :
Immunogen: Recombinant corresponding to 243aa and 5 extra aa of human Myostatin Propeptide expressed in E. coli (28kD).
products categories :
Antibodies; Abs to Peptides
products description :
Myostatin (GDF 8) is expressed uniquely in human skeletal muscle as a 12kD mature glycoprotein consisting of 109 aa residues and secreted into plasma. Myostatin is a member of the transforming growth factor beta superfamily of secreted growth and differentiation factors that is essential for proper regulation of skeletal muscle mass. Studies have shown that myostatin could play an important role in cardiac development and physiology. In serum, myostatin circulates as part of a latent complex containing myostatin propeptide and/or follistatin-related gene. The myostatin propeptide is known to bind and inhibit myostatin in vitro. This interaction is relevant in vivo, with a majority (>70%) of myostatin in serum bound to its propeptide. The myostatin propeptide is negative regulator of myostatin in vivo.
ncbi acc num :
ADD12958.1