catalog number :
MBS616938
products full name :
Homocysteine, Conjugated
products short name :
Homocysteine, Conjugated
products name syn :
Anti -Homocysteine, Conjugated
specificity :
Recognizes protein-conjugated homocysteine. Exhibits very low affinity towards free homocysteine.
purity :
Purified. Antiserum previously preabsobed on protein carriers, and purified
form :
Supplied as a liquid in PBS, pH 7.2. No preservative added.
storage stability :
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile ddH2O or PBS. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
tested application :
ELISA (EL/EIA), Immunocytochemistry (ICC), Gel Shift Assay (GS/EMSA)
app notes :
Suitable for use in ELISA, Immunohistochemistry and Dot Blot.
other info1 :
Immunogen: A synthetic peptide conjugated Homocysteine to protein carrier (Pc).
products categories :
Antibodies; Abs to Amino Acids
products description :
Homocysteine a sulfur containing amino acid, is formed by the transmethylation of methionine, an essential amino acid. Homocysteine may be irreversibly metabolized to cystathionine by cystathionine synthetase. This reaction uses pyridoxal phosphate (Vitamin B6) as a co-enzyme. The enzyme cystathionine synthetase is deficient in homocysteinuria, a rare genetic disease associated with high blood levels of homocysteine and the development of premature atherosclerosis. This and the association of other rare enzyme deficiencies with homocysteinemia and premature atherosclerosis led McCully to formulate the homocysteine hypothesis of atherosclerosis (McCully, K.S., The homocysteine theory of atherosclerosis. Atherosclerosis 20: 23-27 (1976)).