antibody

Neurotensin Receptor 1 (NTR1)

MBS613670

0.1 mg

745 USD

polyclonal

rabbit

nonconjugated

human, mouse

western blot, ELISA, immunohistochemistry, enzyme immunoassay

Antibody

Neurotensin Receptor 1 (NTR1)

[Neurotensin Receptor 1]

[Anti -Neurotensin Receptor 1 (NTR1)]

[neurotensin/neuromedin N preproprotein; Neurotensin/neuromedin N; neurotensin/neuromedin N; pro-neurotensin/neuromedin; neurotensin; NmN-125]

[NTS; NTS; NN; NT; NT/N; NTS1; NMN-125; NN; NmN; NT]

NEUT_HUMAN

Polyclonal

IgG

Rabbit

Mouse

Recognizes mouse NTR1. No significant sequence homology exist with NTR2 or NTR3 or other GPCR.

Affinity Purified. Purified by immunoaffinity chromatography.

Supplied as a liquid in PBS, pH 7.4 and 0.1% BSA.

1mg/ml

May be stored at 4 degree C for short-term only. For long-term storage, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)

Suitable for use in ELISA, Immunohistochemistry and Western Blot. Dilution: Western Blot: 1-10ug/ml (ECL). ELISA: ~1:100,000 using 50-100ng control peptide/well. Immunohistochemistry: 2-20ug/ml, formaldehyde fixed tissue.

Immunogen: An 18-aa peptide sequence within the extracellular, mid-region of mouse NTR1 (KLH). Species Sequence Homology: Human, Rat: 84%

Antibodies; Abs to Receptors

5453816

NP_006174.1

NM_006183.4

P30990

19,795 Da

Class A/1 (Rhodopsin-like Receptors) Pathway (106357); G Alpha (q) Signalling Events Pathway (106043); GPCR Downstream Signaling Pathway (119548); GPCR Ligand Binding Pathway (161020); Gastrin-CREB Signalling Pathway Via PKC And MAPK (645295); Peptide Ligand-binding Receptors Pathway (106358); Signal Transduction Pathway (477114); Signaling By GPCR Pathway (106356)

This gene encodes a common precursor for two peptides, neuromedin N and neurotensin. Neurotensin is a secreted tridecapeptide, which is widely distributed throughout the central nervous system, and may function as a neurotransmitter or a neuromodulator. It may be involved in dopamine-associated pathophysiological events, in the maintenance of gut structure and function, and in the regulation of fat metabolism. Tissue-specific processing may lead to the formation in some tissues of larger forms of neuromedin N and neurotensin. The large forms may represent more stable peptides that are also biologically active. [provided by RefSeq, Jul 2008]

NTS: Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism. It causes contraction of smooth muscle. Belongs to the neurotensin family. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 12q21. Cellular Component: transport vesicle; extracellular region. Molecular Function: neuropeptide hormone activity; protein binding. Biological Process: regulation of blood vessel size; signal transduction

0.1 mg

745 USD