catalog number :
MBS613178
products full name :
PLTP (Plasma Phospholipid Transfer Protein)
products short name :
PLTP
products name syn :
Anti -PLTP (Plasma Phospholipid Transfer Protein)
other names :
phospholipid transfer protein isoform b; Phospholipid transfer protein; phospholipid transfer protein; OTTHUMP00000031678; OTTHUMP00000031679; OTTHUMP00000214864; OTTHUMP00000214865; OTTHUMP00000214866; lipid transfer protein II; phospholipid transfer protein; Lipid transfer protein II
other gene names :
PLTP; PLTP; HDLCQ9; N/A
uniprot entry name :
PLTP_HUMAN
host :
Host: Rabbit; Source: Human
reactivity :
Human, Mouse
specificity :
Specific for human Phospholipid Transfer Protein (PLTP), ~78kD. Based on sequence homology, is expected to recognize mouse PLTP.
form :
Supplied as a liquid in 0.02% sodium azide.
storage stability :
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
tested application :
Western Blot (WB)
app notes :
Suitable for use in Western Blot (non-neutralizing). This antibody does not exhibit neutralizing activity. Dilution: Western Blot: 1:500-1:1000
other info1 :
Immunogen: aa470-490 of human PLTP (EVIEKNRPADVRASTAPTPST)
products categories :
Antibodies; Abs to Serum Proteins
products description :
Plasma phospholipid transfer protein (PLTP) plays a central role in regulating plasma HDL levels and distribution of HDL subpopulations. This regulation is evidenced in vivo by markedly reduced plasma HDL levels in PLTP gene knock-out mice. PLTP also facilitates free cholesterol influx into HDL.
ncbi acc num :
NP_872617.1
ncbi gb acc num :
NM_182676.2
ncbi mol weight :
54,739 Da
ncbi pathways :
Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway 160977!!HDL-mediated Lipid Transport Pathway 106158!!Lipid Digestion, Mobilization, And Transport Pathway 106111!!Lipoprotein Metabolism Pathway 106156!!Metabolism Of Lipids And Lipoproteins Pathway 160976!!PPAR Signaling Pathway 83042!!PPAR Signaling Pathway 450!!Regulation Of Lipid Metabolism By Peroxisome Proliferator-activated Receptor Alpha (PPARalpha) Pathway 119544!!Statin Pathway 198852
ncbi summary :
The protein encoded by this gene is one of at least two lipid transfer proteins found in human plasma. The encoded protein transfers phospholipids from triglyceride-rich lipoproteins to high density lipoprotein (HDL). In addition to regulating the size of HDL particles, this protein may be involved in cholesterol metabolism. At least two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
uniprot summary :
Function: Converts HDL into larger and smaller particles. May play a key role in extracellular phospholipid transport and modulation of hdl particles. Subcellular location: Secreted. Tissue specificity: Wide tissue distribution. Placenta > pancreas > lung > kidney > heart > liver > skeletal muscle > brain. Sequence similarities: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.