catalog number :
MBS612400
products full name :
Nuclear Coactivator Protein, p100
products short name :
Nuclear Coactivator Protein, p100
products name syn :
Anti -Nuclear Coactivator Protein, p100
reactivity :
Bovine, Drosophila, Human, Mouse, Rat
specificity :
Recognizes human p100 Nuclear Coactivator Protein. Reactive on BMGE (bovine mammary epithelial cells). Species Crossreactivity: bovine, rat, mouse, drosophila.
form :
Supplied as a liquid, 0.09% sodium azide.
storage stability :
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
tested application :
Western Blot (WB), Immunofluorescence (IF)
app notes :
Suitable for use in Western Blot and Immunofluorescence. Dilution: Western Blot (ECL): 1:2000. Immunofluorescence (frozen): 1:100-1:200. Incubate for 1hr at RT.
other info1 :
Immunogen: Synthetic peptide corresponding to the C-terminus of human p100 protein (KLH).
products categories :
Antibodies; Abs to Proteins
products description :
p100 is a ubiquitously expressed protein highly conserved during evolution that has been described as a coactivator that enhances the transcriptional activity of EBNA2 of EBV, functions as a bridging factor between STAT6 and the basal transcription machinery bridges, and interacts with the large subunit of RNA polymerase II (1). Antibody studies have localized p100 in the ER and lipid droplets of milk secreting cells. In addition to its nuclear localization, the p100 protein was also detected in cytosolic fractions from lactating mammary gland, in storage lipid droplets from adipocytes, and in ER from liver (2).