catalog number :
MBS612102
products full name :
a-Tocopherol (Vitamin E), Conjugated
products short name :
a-Tocopherol
products name syn :
Anti -a-Tocopherol (Vitamin E), Conjugated
other names :
alpha-tocopherol transfer protein; Alpha-tocopherol transfer protein; alpha-tocopherol transfer protein; alpha-TTP; Tocopherol transfer protein alpha; tocopherol (alpha) transfer protein
other gene names :
Ttpa; Ttpa; TTP; Tpp1
uniprot entry name :
TTPA_RAT
specificity :
Recognizes protein-linked alpha-Tocopherol (vitamin E). ELISA test results:
purity :
Purified. Antiserum previously preabsobed on protein carriers, and purified by ammonium sulfate precipitation and gel filtration.
form :
Supplied as a liquid, pH 7.2. No preservative added.
storage stability :
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
tested application :
ELISA (EL/EIA), Immunohistochemistry (IHC)
app notes :
Suitable for use in ELISA and Immunohistochemistry. Dilution: Immunohistochemistry: 1:500-1:2000
other info1 :
Immunogen: Synthetic alpha-Tocopherol acid succinate, conjugated with BSA.
products categories :
Antibodies; Abs to Vitamins
products description :
alpha-Tocopherol is a form of vitamin E that is preferentially absorbed and accumulated in humans. The measurement of "vitamin E" activity in international units (IU) was based on fertility enhancement by the prevention of spontaneous abortions in pregnant rats relative to alpha-Tocopherol.
ncbi acc num :
NP_037180.1
ncbi gb acc num :
NM_013048.2
ncbi mol weight :
31,846 Da
ncbi summary :
binds the vitamin tocopherol and enhances its transfer between separate membranes [RGD, Feb 2006]
uniprot summary :
TTPA: Binds alpha-tocopherol and enhances its transfer between separate membranes. Defects in TTPA are the cause of ataxia with isolated vitamin E deficiency (AVED). AVED is an autosomal recessive disease characterized by spinocerebellar degeneration. It causes ataxia and peripheral neuropathy that resembles Friedreich ataxia. AVED patients have markedly reduced plasma levels of vitamin E. Protein type: Transporter. Cellular Component: late endosome; cytosol. Molecular Function: phosphatidylinositol-4,5-bisphosphate binding; transporter activity; vitamin binding; phosphatidylinositol-3,4-bisphosphate binding; vitamin E binding. Biological Process: vitamin E metabolic process; embryonic placenta development; response to toxin; intracellular pH reduction; intermembrane transport; vitamin transport; developmental process; response to nutrient; response to pH; placenta development