product summary
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company name :
MyBioSource
product type :
antibody
product name :
GABA Receptor B 1b (GBR1b)
catalog :
MBS611586
quantity :
0.05 mg
price :
400 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
mouse, rat, zebrafish
application :
western blot, ELISA, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS611586
products type :
Antibody
products full name :
GABA Receptor B 1b (GBR1b)
products short name :
GABA Receptor B 1b
products name syn :
Anti -GABA Receptor B 1b (GBR1b)
other names :
Gabarap protein, partial; GABA(A) receptor-associated protein; GABA(A) receptor-associated protein; GABA(A) receptor associated protein; GABA(A) receptor-associated protein a
other gene names :
gabarapa; gabarap; mg:bb02b03
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Mouse, Rat
specificity :
Recognizes rat GBR1b. Peptide sequence is 100% conserved in various alternatively spliced rat GBR1b (844aa), GBR1c (875aa) and GBR1d (812aa). No significant sequence homology is detected with GBR1a or GBR2 or other GABA receptors.
purity :
Affinity Purified. Purified by immunoaffinity chromatography.
form :
Supplied as liquid in PBS, 0.1% BSA, 0.05% sodium azide.
concentration :
1mg/ml
storage stability :
May be stored at 4 degree C for short-term only. For long-term storage, store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
tested application :
ELISA (EL/EIA), Western Blot (WB)
app notes :
Suitable for use in ELISA and Western Blot. Dilution: Western Blot: 1-10ug/ml (ECL). ELISA: 0.5-1ug/ml. Control peptide can be used to coat ELISA plates at 1ug/ml.
other info1 :
Immunogen: Synthetic peptide corresponding to a 16aa sequence near the N-terminus, extracellular domain of rat GBR1b, conjugated to KLH. Species Sequence Homology: Mouse: 100%. Human: 93%
products categories :
Antibodies; Abs to Receptors
products description :
GABA (g-amino butyric acid) is the most abundant neurotransmitter in mammalian brain. GABA exerts its effects through ionotropic ligand-gated GABAA, GABAC and GABAB receptors (GABABRs). Presynaptic GABABRs inhibit neurotransmitter release by down regulating high voltage activated Ca+2 channels, whereas postsynaptic GABABRs decrease neuronal excitability by activating a prominent inwardly rectifying K+ (Kir) conductance that underlies the late inhibitory postsynaptic potential. Two N-terminal splice variants GABABR1 (also called GBR1), GABABR1a (GBR1a, rat 960aa, apparent mol wt ~130kD; human 961aa) and GABABR1b (GBR1b; rat 844aa, apparent MW 100kD; human 844aa) have been cloned and characterized. GABABRs are characterized by the presence of a cleavable signal peptide, a large extracellular N-terminus, 7 TM domains, and C-terminal, cytoplasmic domain. GABABRs are expressed in all major areas of the brain. Recently GABABR2 (or GBR2) has been cloned from rat (940aa) and human (941aa). GBR2 forms heterodimer with GBR1 through interaction at the intracellular C-terminal regions. Heterodimerization appears to be important in transporting GBR1 to the membrane and expression of functional receptors. GBR2 also co-localized with GBR1.
ncbi gi num :
34784077
ncbi acc num :
AAH56701.1
ncbi pathways :
Regulation Of Autophagy Pathway (83635); Regulation Of Autophagy Pathway (468)
size1 :
0.05 mg
price1 :
400 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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