product summary
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company name :
MyBioSource
product type :
antibody
product name :
Period Clock Protein (dPER)
catalog :
MBS610421
quantity :
0.05 mL
price :
460 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
fruit fly
application :
western blot, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS610421
products type :
Antibody
products full name :
Period Clock Protein (dPER)
products short name :
[Period Clock Protein]
products name syn :
[Anti -Period Clock Protein (dPER)]
other names :
[period, isoform B; CG2647 gene product from transcript CG2647-RA; CG2647-PA; CG2647-PB; PERIOD; clock; clock-6; dperiod; per-PA; per-PB; period clock protein; period]
other gene names :
[per; CG2647; Clk; clk-6; DmelCG2647; dmper; dper; dPER; EG:155E2.4; mel_per; Per; PER]
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Drosophila
specificity :
Recognizes drosophila Period Clock Protein.
purity :
Serum
form :
Supplied as a liquid in PBS, 0.05% sodium azide.
storage stability :
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
tested application :
suitable for use in ELISA (EL/EIA), Western Blot (WB).
app notes :
Western Blot: 1:1000-1:5000 (ECL). ELISA : 1:10,000-1:100,000 using 50-100 ng of control peptide/well. Optimal dilutions to be determined.
other info1 :
Immunogen: A 21-aa peptide sequence within C-terminus of dPer (1) was synthesized coupled to KLH
other info2 :
Grade: serum. Control Peptide: Period Clock Protein, Rabbit, Control Peptide (dPER)
products categories :
Antibodies; Abs to Circadian Proteins
products description :
Several endogenous factors have been linked to rhythmicity or circadian behavior of living organisms. In Drosophila, the genes period (dPer) and timeless (tim), and in Neurospora frequency (frq), have been proposed to be responsible for their circadian rhythm. Recently human and mouse genes encoding a basichelix-loop-helix (bHLH) and Per-ARNT-Sim (PAS)-domain with significant similarity to the Drosophila Period have been reported. The cDNA sequences of hPER and mPer1 (also named RIGUI) are predicted to encode for proteins of length 1290 and 1291 amino acids respectively. Homologues of mPer1 designated Per 2 (1257 aa) and Per3 (1113 aa) have also been cloned. Both Per1 and Per2 levels show circadian rhythm in the SCN and eyes. It has been suggested that mPer regulates neuronal activity in the SCN. Using genetic approach, a single mutation (A to T in the Clock gene affects circadian rhythmicity in mice. Clock has been mapped to chromosome 5. Mouse Clock encodes a transcription factor, a single polypeptide chain of 855 aa (predicted calculated mol wt ~97kD; pI 6.52; hClock, 846 aa). Clock is abundantly expressed in brain (SCN, pyrifom cortex, hippocampus) as well as in other tissues (eye, total brain, tested, ovaries, liver, heart, lung, and kidney). Although, Clock is constitutively expressed (not rhythmic) in the SCN, it may still be an important component of circadian machinery.
ncbi gi num :
442614977
ncbi acc num :
NP_001259194.1
ncbi gb acc num :
NM_001272265.1
ncbi pathways :
BMAL1:CLOCK/NPAS2 Activates Circadian Expression Pathway (824620); Circadian Clock Pathway (824619); Circadian Rhythm - Fly Pathway (95646)
size1 :
0.05 mL
price1 :
460 USD
size2 :
0.1 mL
price2 :
720
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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