antibody

Mouse anti-Human Phosphatase, Alkaline, Human, Bone (BAP)

MBS609529

0.2 mg

515 USD

monoclonal

mouse

nonconjugated

0.G.2

western blot, ELISA, enzyme immunoassay

Antibody

Mouse anti-Human Phosphatase, Alkaline, Human, Bone (BAP)

Phosphatase, Alkaline, Bone

Anti -Phosphatase, Alkaline, Human, Bone (BAP)

Monoclonal

IgG1

0.G.2

Mouse

Alkaline phosphatase from human placenta, calf intestine and bacterial.

Recognizes Alkaline Phosphatase from human bone.

Affinity Purified. Purified by Protein A affinity chromatography.

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

1mg/ml

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

ELISA (EL/EIA), Western Blot (WB)

Suitable for use in ELISA and Western Blot. Dilution: Western Blot: Stains a band of bone AP at ~90kD.

Immunogen: Purified alkaline phosphatase (native) from human bone.

Antibodies; Abs to Enzymes, Phosphatase

Alkaline phosphatase (AP) is a ubiquitously expressed enzyme which removes phosphate groups from target molecules, including DNA, RNA and alkaloids, under alkaline conditions, and is present at higher concentrations in the placenta (placental AP), intestines (intestinal AP) and liver/bone/kidney (tissue non-specific AP). Although the exact biochemical function of BAP is uncertain, measurement of the serum levels of BAP can be used as a biochemical indicator of bone turnover. Conditions which present with a decrease in the level of BAP (hypophosphatasemia) include the inherited bone-deforming disorder hypophosphatasia and osteoporosis, while an increase in BAP (hyperphosphatasemia) is associated with Paget's disease, bone fractures and osteosarcomas.

0.2 mg

515 USD