catalog number :
MBS608181
products full name :
Polymyxin B
products short name :
[Polymyxin B]
products name syn :
[Anti -Polymyxin B]
other names :
[polymyxin B resistance protein; polymyxin B resistance protein]
other gene names :
[pmrD]
specificity :
Recognizes Polymyxin B. Binds to free Polymyxin B as well as to Polymyxin B already bound to LPS.
form :
Supplied as a liquid, 0.02% sodium azide.
storage stability :
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
tested application :
ELISA (EL/EIA), Western Blot (WB)
app notes :
Western Blot: 1:10. Optimal dilutions to be determined by the researcher.
other info1 :
Immunogen: Whole bacteria of the Re chemotype of S. minnesota
products categories :
Antibodies; Abs to Antibiotics
products description :
The peptide antibiotic Polymyxin B (PMB) binds to bacterial endotoxin (lipopolysaccharide, LPS). The interaction of PMB with LPS involves ionic forces between amino groups in PMB and negatively charged phosphate and carboxyl groups in the lipid A-Kdo region. PMB has relevance for endotoxin research in at least two ways: first, PMB reacts with LPS of many species regardless of varied serospecificity, and thus it can be used as a general probe for measuring or detecting LPS or lipid A. Second, binding of PMB to LPS may result in neutralization of the detrimental effects of LPS either in vitro or in vivo. Monoclonal antibody enables the possibilities to study quantitatively the interaction of PMB and LPS.
ncbi acc num :
NP_456847.1
ncbi gb acc num :
NC_003198.1