product summary
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company name :
MyBioSource
product type :
antibody
product name :
Verotoxin II A subunit (Shiga-like toxin 2 subunit A, SLT-2a, SLT-IIa)
catalog :
MBS606171
quantity :
0.1 mg
price :
780 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
[9G301]
more info or order :
product information
catalog number :
MBS606171
products type :
Antibody
products full name :
Verotoxin II A subunit (Shiga-like toxin 2 subunit A, SLT-2a, SLT-IIa)
products short name :
[Verotoxin II A subunit]
products name syn :
[Anti -Verotoxin II A subunit (Shiga-like toxin 2 subunit A, SLT-2a, SLT-IIa)]
clonality :
Monoclonal
isotype :
IgG1
clone :
[9G301]
host :
Mouse
specificity :
Recognizes the 2A subunit of Shiga-like toxin 2
purity :
Purified by Protein G affinity chromatography
form :
Supplied as a liquid in PBS, 0.1% BSA
concentration :
0.1 mg/ml
storage stability :
May be stored at 4°C for short term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
tested application :
Suitable for use in Western Blot (WB), ELISA (EIA) and Functional Assays. Other applications not tested.
app notes :
Western Blot (WB): 1:10. ELISA (EIA) 1:10. Optimal dilutions to be determined by the researcher.
other info1 :
Grade: Affinity purified. Endotoxin: <0.4 mg/ml
products categories :
Antibodies; Abs to Infectious Disease
products description :
Shiga-like toxins (SLTs), are also called Verotoxins. Enterohemorrhagic Escherichia coli (EHEC) strains which are primarily of serotypes 0157:H7, 026:H11, and O111:H8 have been incriminated as etiologic agents of hemorrhagic colitis and Hemolytic-uremic syndrome, a generalized disease characterized by acute renal failure, thrombocytopenia, and microangiopathic hemolytic anemia. There are several distinct E.coli SLTs. SLT-I and SLT-II are produced by EHEC. SLT-I and Shiga toxin share >99% deduced amino acid sequence homology, whereas SLT-I and SLT-II share about 60% deduced amino acid sequence homology. SLT-I and SLT-II are antigenically distinct. Antibodies to SLT-II can also neutralize a variant of SLT-II (designated SLT-Iiv) produced by strains of E.coli that cause edema. SLT-IIv is cytotoxic for Vero but not HeLa cells, distinguishing it from SLT-II. The protein structure of the toxin consists of two domains: the A polypeptide that inhibits protein synthesis by targeting ribosomes, and the B polypeptide pentamer that binds to the eukaryotic cell receptor globotriaosylceramide (Gb3) leading to receptor-mediated endocytosis.
size1 :
0.1 mg
price1 :
780 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
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