Ras, pan, N,H,K | MyBioSource MBS605436 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Ras, pan, N,H,K

catalog :

MBS605436

quantity :

0.1 mL

price :

465 USD

clonality :

monoclonal

host :

rabbit

conjugate :

nonconjugated

clone name :

7H56

reactivity :

human, mouse, rat, fruit fly

application :

western blot, ELISA, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS605436

products type :

Antibody

products full name :

Ras, pan, N,H,K

products short name :

Ras, pan, N,H,K

products name syn :

Anti -Ras, pan, N,H,K

other names :

Ras oncogene at 85D; CG9375 gene product from transcript CG9375-RA; CG9375-PA; Ras GTPase; Ras oncogene at 85B; Ras oncogene at 85D; Ras1; Ras85D-PA; enhancer of faf; Ras oncogene at 85D

other gene names :

Ras85D; C-ras1; CG9375; D-Ras; D-ras-1; D-ras1; D-Ras1; Dm Ras1; DmelCG9375; Dmras85D; dRas; Dras; DRas; dras1; dRas1; dRAS1; Dras1; DRAS1; dRas85D; Dras85D; DRas85D/Ras; E(faf); E(sev)3C; EK3-4; fs(3)05703; l(3)06677; l(3)s1747; p21[Ras1]; ras; Ras; RAS; ras 1;

clonality :

Monoclonal

isotype :

IgG

clone :

7H56

host :

Rabbit

reactivity :

Drosophila, Human, Monkey, Mouse, Rat, Yeast

specificity :

Recognizes endogenous levels of human total K-Ras, H-Ras and N-Ras proteins at ~21kD. Species Crossreactivity mouse, monkey, rat, Drosophila, S. cerevisiae.

purity :

Supernatant. Supernatant

form :

Supplied as a liquid in 10mM sodium HEPES, pH 7.5, 150mM sodium chloride, 0.1mg/ml BSA, <0.02% sodium azide, 50% glycerol.

storage stability :

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

tested application :

ELISA (EL/EIA), Western Blot (WB)

app notes :

Suitable for use in ELISA and Western Blot. Dilution: Western Blot: 1:1000

other info1 :

Immunogen: Synthetic peptide corresponding to residues near the amino terminus of human K-Ras (KLH).

products categories :

Antibodies; Abs to Cancer Markers

products description :

The 21kD guanine-nucleotide binding proteins (K-Ras, H-Ras and N-Ras) cycle between active (GTP-bound) and inactive (GDP-bound) forms. Receptor tyrosine kinases and G-protein-coupled receptors activate Ras, which then stimulates the Raf-MEK-MAPK pathway. GTPase-activating proteins (GAP) normally facilitate the inactivation of Ras. However, in 30% of human tumors, point mutations in Ras prevent the GAP-mediated inhibition of this pathway. The most common oncogenic Ras mutation found in tumors is Gly12 to Asp (G12D), which prevents Ras inactivation, possibly by increasing the overall rigidity of the protein.

ncbi gi num :

17136430

ncbi acc num :

NP_476699.1

ncbi gb acc num :

NM_057351.5

ncbi pathways :

ARMS-mediated Activation Pathway (824068); Axon Guidance Pathway (824307); Cytokine Signaling In Immune System Pathway (824551); DAP12 Interactions Pathway (824545); DAP12 Signaling Pathway (824546); Developmental Biology Pathway (824306); Disease Pathway (823917); Dorso-ventral Axis Formation Pathway (3095); Dorso-ventral Axis Formation Pathway (472); Downstream Signal Transduction Pathway (824077)

size1 :

0.1 mL

price1 :

465 USD

more info or order :

MyBioSource product webpage

company information

MyBioSource

P.O. Box 153308
San Diego, CA 92195-3308

sales@mybiosource.com

https://www.mybiosource.com

1-888-627-0165

headquarters: USA

MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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