catalog number :
MBS604737
products full name :
a1-Acid Glycoprotein (Orosomucoid)
products short name :
a1-Acid Glycoprotein
products name syn :
Anti -a1-Acid Glycoprotein (Orosomucoid)
other names :
alpha-1-acid glycoprotein; Alpha-1-acid glycoprotein; alpha-1-acid glycoprotein; orosomucoid 1; Orosomucoid
other gene names :
Orm1; Orm1; AGP; OMD; Orm; Agpa1
uniprot entry name :
A1AG_RAT
specificity :
Recognizes human Alpha-1 acid glycoprotein.
purity :
Affinity Purified. Purified by Protein G affinity chromatography.
form :
Supplied as a lyophilized powder in 0.2um sterile-filtered solution in PBS, 5% trehalose. Reconstitute with 200ul sterile PBS.
storage stability :
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
tested application :
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
Dilution: Direct ELISA: 0.5-1ug/ml; The detection limit is ~1ng/well. Western Blot: 1-2ug/ml; Detects human AGP in cell or tissue extracts. Buffers used are as follows:. Blotting buffer - 25mM Tris, pH 7.4, 0.15M sodium chloride, 0.05% Tween -20. Blocking solution - 5% nonfat dry milk in Blotting buffer. Antibody solution - 5% nonfat dry milk in Blotting buffer. Immunohistochemistry (Paraffin): 25ug/ml; Stains paraffin-embedded normal human liver sections. Optimal dilutions to be determined by the researcher
other info1 :
Immunogen: Human AGP from plasma.
products categories :
Antibodies; Abs to Carbohydrates, Glycoproteins
products description :
Alpha-1 acid glycoprotein (AGP), also known as orosomucoid-1, is an acute phase protein secreted by the liver. Serum AGP levels are elevated during inflammatory responses. AGP binds a wide range of molecules in the circulation. Human and mouse AGP share 43% amino acid sequence identity.
ncbi acc num :
NP_445740.1
ncbi gb acc num :
NM_053288.1
ncbi mol weight :
23,575 Da
ncbi summary :
an acute phase reactant protein; may have a role in the acute inflammation response [RGD]
uniprot summary :
ORM1: Functions as transport protein in the blood stream. Binds various ligands in the interior of its beta-barrel domain. Also binds synthetic drugs and influences their distribution and availability in the body. Appears to function in modulating the activity of the immune system during the acute-phase reaction. Belongs to the calycin superfamily. Lipocalin family. Protein type: Secreted, signal peptide; Secreted. Cellular Component: extracellular space. Molecular Function: drug binding. Biological Process: response to drug; response to vitamin E; organ regeneration; regulation of immune system process; transport; acute-phase response; response to lipopolysaccharide; chronic inflammatory response to antigenic stimulus; response to organic cyclic substance; acute inflammatory response to antigenic stimulus