catalog number :
MBS603569
products full name :
CTRP1 (C1q Tumor Necrosis Factor alpha Related Protein 1, C1qTNF1)
products short name :
[CTRP1]
products name syn :
[Anti -CTRP1 (C1q Tumor Necrosis Factor alpha Related Protein 1, C1qTNF1)]
other names :
[complement C1q tumor necrosis factor-related protein 1 isoform 1; Complement C1q tumor necrosis factor-related protein 1; complement C1q tumor necrosis factor-related protein 1; G protein coupled receptor interacting protein; g protein-coupled receptor-interacting protein; C1q and tumor necrosis factor related protein 1; G protein-coupled receptor-interacting protein]
other gene names :
[C1QTNF1; C1QTNF1; GIP; CTRP1; ZSIG37; FLJ90694; CTRP1]
uniprot entry name :
C1QT1_HUMAN
specificity :
Recognizes human CTRP1. Does not crossreact with recombinant human CTRP4, CTRP5 or CTRP10.
purity :
Purified by Protein G affinity chromatography.
form :
Supplied as a lyophilized powder from PBS, 5% trehalose. Reconstitute with 200ul sterile PBS.
concentration :
~0.5mg/ml (after reconsitution)
storage stability :
Lyophilized and reconstituted products are stable for 12 months after receipt at -20 degree C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
tested application :
ELISA (EL/EIA), Western Blot (WB)
app notes :
Dilution: Western Blot: 1-2ug/ml. Using a colormetric detection system, the detection limit is ~5ng/lane under non-reducing and reducing conditions. ELISA (Direct): 0.5-1ug/ml. The detection limit is ~1ng/well. Optimal diulutions to be determined by the researcher.
other info1 :
Immunogen: Recombinant protein corresponding to aa26-281 from human CRTP1, expressed in NSO cells.; Species Sequence Homology: mouse 78%
other info2 :
Grade: Affinity Purified
products categories :
Antibodies; Abs to Obesity Proteins
products description :
CTRP1 belongs to the highly conserved family of Acrp30/Adiponectin paralogs known as the C1q and TNF-related protein family. All family members share a modular organization comprising an N-terminal signal peptide, a short variable region, a collagenous domain and a C-terminal globular domain. CTRP1 proteins are predicted to have trimeric structures that assemble into hexameric and higher order molecular forms.
ncbi acc num :
NP_940995.1
ncbi gb acc num :
NM_198593.2
uniprot summary :
C1QTNF1: 2 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 17q25.3. Cellular Component: extracellular space; collagen; integral to plasma membrane. Molecular Function: collagen binding; protein binding. Biological Process: positive regulation of protein kinase B signaling cascade; elevation of cytosolic calcium ion concentration; positive regulation of MAPKKK cascade; protein homooligomerization