catalog number :
MBS603470
products full name :
Mycobacterium tuberculosis CFP10
products short name :
[Mycobacterium tuberculosis CFP10]
products name syn :
[Anti -Mycobacterium tuberculosis CFP10]
specificity :
Recognizes the CFP10 antigen of Mycobacterium tuberculosis.
purity :
Affinity Purified. Purified by Protein G chromatography. >95% pure.
form :
Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide.
storage stability :
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
tested application :
ELISA (EL/EIA)
app notes :
Suitable for use in ELISA. Other applications have not been tested. Optimal dilutions to be determined by the researcher.
other info1 :
Immunogen: Recombinant protein CFP10 M. tuberculosis H37RV.
other info2 :
Hybridoma: Sp2/0 myeloma cells with spleen cells from Balb/c mice.
products categories :
Antibodies; Abs to Infectious Disease Mycobacterium
products description :
Mycobacterium tuberculosis is the most common cause of tuberculosis. Primary infection begins with inhalation of 1 to 10 aerosolised bacilli. The pathogenicity of the organism is determined by its ability to escape host immune responses as well as eliciting delayed hypersensitivity. Alveolar macrophages engulf the invading cells but are unable to mount an effective defense. Several virulence factors are responsible for this apparent failure; most notably in the mycobacterial cell wall are the cord factor, lipoarabinomannan, and the 65kD heat shock protein or HSP65. The emergence of new strains of resistant Mycobacterium tuberculosis has created new interest in clinical diagnosis. Studies have shown immunohistochemical techniques to be superior to conventional special stains. Thus the demonstration of mycobacterial antigens are not only useful in establishing mycobacterial aetiology, but can also be used as an alternative method to the conventional Ziehl-Neelsen method.