catalog number :
MBS603386
products full name :
ACTH, NT (Adrenocorticotropic Hormone, Adrenocorticotropin, Corticotropin)
products short name :
[ACTH]
products name syn :
[Anti -ACTH, NT (Adrenocorticotropic Hormone, Adrenocorticotropin, Corticotropin)]
specificity :
Recognizes human Adrenocorticotrophic Hormone (ACTH). Shows broad species crossreactivity.
purity :
Affinity Purified. Purified by Protein G affinity chromatography.
form :
Supplied as a liquid in 10mM PBS, pH 7.4, 0.2% BSA, 15mM sodium azide. Also available without BSA and azide.
storage stability :
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
tested application :
ELISA (EL/EIA), Immunohistochemistry (IHC)
app notes :
Suitable for use in ELISA and Immunohistochemistry. Dilution: Immunohistochemistry (Formalin/paraffin): 0.2-0.4ug/ml. Incubate 30 minutes at RT. No special pretreatment required for staining.
image1 heading :
Immunohistochemistry (IHC)
other info1 :
Immunogen: Synthetic peptide corresponding to aa1-24 from the N-terminal of human ACTH. Cellular Localization: Cytoplasmic
other info2 :
Positive Control: Normal pituitary glad or pituitary adenoma
products categories :
Antibodies; Abs to Hormones, Steroids
products description :
Adrenocorticotropic hormone (ACTH), also known as corticotropin, is a polypeptide tropic hormone produced and secreted by the anterior pituitary gland. It is an important component of the hypothalamic-pituitary-adrenal axis and is often produced in response to biological stress (along with its precursor corticotropin-releasing hormone from the hypothalamus). Its principal effects are increased production and release of corticosteroids. A deficiency of ACTH is a cause of secondary adrenal insufficiency and an excess of it is a cause of Cushing's disease.
ncbi pathways :
Focal Adhesion Pathway (83067); Focal Adhesion Pathway (478); MAPK Signaling Pathway (83048); MAPK Signaling Pathway (456); Salmonella Infection Pathway (375172); Salmonella Infection Pathway (375149)