product summary
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company name :
MyBioSource
product type :
antibody
product name :
LAIR-2 (Leukocyte-associated Ig-like Receptor-2)
catalog :
MBS603173
quantity :
0.1 mg
price :
655 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
[7H82]
reactivity :
human
application :
western blot, flow cytometry, FACS
more info or order :
image
image 1 :
Jurkat cells were stained with MBS603173 (filled histogram) or isotype control (open hisotgram) followed by APC-conjugated goat anti-mouse IgG.
product information
catalog number :
MBS603173
products type :
Antibody
products full name :
LAIR-2 (Leukocyte-associated Ig-like Receptor-2)
products short name :
[LAIR-2]
products name syn :
[Anti -LAIR-2 (Leukocyte-associated Ig-like Receptor-2)]
other names :
[leukocyte-associated immunoglobulin-like receptor 2 isoform a; Leukocyte-associated immunoglobulin-like receptor 2; leukocyte-associated immunoglobulin-like receptor 2; LAIR-2; OTTHUMP00000068389; OTTHUMP00000068390; leukocyte-associated Ig-like receptor 2; leukocyte-associated Ig-like receptor-2; leukocyte-associated immunoglobulin-like receptor 2]
other gene names :
[LAIR2; CD306; MGC71634]
uniprot entry name :
LAIR2_HUMAN
clonality :
Monoclonal
isotype :
IgG2b
clone :
[7H82]
host :
Mouse
reactivity :
Human
specificity :
Recognizes human LAIR-2. Does not recognize recombinant human LAIR-1 or recombinant mouse LAIR-1 or LAIR-2
purity :
Affinity Purified. Purified by Protein A affinity chromatography.
form :
Supplied as a lyophilized powder from PBS, pH7.4, 5% trehalose. Reconstitute with 200ul sterile PBS.
concentration :
~0.5mg/ml(after reconstitution)
storage stability :
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
tested application :
Western Blot (WB), Flow Cytometry (FC/FACS)
app notes :
Western Blot: 1ug/ml. Flow Cytometry (Intracellular): 2.5ug/10e6 cells using Jurkat human acute T cell leukemia cell line fixed with paraformaldehyde and permeabilized with saponin. Optimal dilutions to be determined by th researcher.
image1 heading :
Testing Data
other info1 :
Immunogen: Recombinant corresponding to Gln22-Pro152 of human LAIR-2 expressed in NSO cells.
other info2 :
Hybridoma: Hybridoma resulting from fusion of mouse myeloma with B cells obtained from a mouse immunized with purified, NS0-derived, recombinant human LAIR-2 (rhLAIR-2; aa22-152; Accession #Q6ISS4).
products categories :
Antibodies; Abs to Receptors
products description :
Leukocyte Associated Ig-like receptor 2 (LAIR2) is a secreted protein that contains one Ig-like domain, which shares 84% amino acid sequence homology with LAIR1. It lacks the transmembrane ITIM-containing cytoplasmic domains of LAIR1. The function of LAIR2 is not known. An alternate splice form of LAIR2 that shows a 17 amino acid deletion outside the Ig domain exists.
ncbi gi num :
10947101
ncbi acc num :
NP_002279.2
ncbi gb acc num :
NM_002288.4
uniprot acc num :
Q6ISS4
ncbi summary :
The protein encoded by this gene is a member of the immunoglobulin superfamily. It was identified by its similarity to LAIR1, an inhibitory receptor present on mononuclear leukocytes. This gene maps to a region of 19q13.4, termed the leukocyte receptor cluster, which contains 29 genes in the immunoglobulin superfamily, including LAIR1. The function of this protein is unknown, although it is thought to be secreted and may help modulate mucosal tolerance. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
uniprot summary :
LAIR-2: 2 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 19q13.4. Cellular Component: extracellular region
size1 :
0.1 mg
price1 :
655 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
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