product summary
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company name :
MyBioSource
product type :
antibody
product name :
b-Amyloid 1-40, 42, CT
catalog :
MBS603141
quantity :
0.1 mg
price :
730 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
[6D4]
application :
enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS603141
products type :
Antibody
products full name :
b-Amyloid 1-40, 42, CT
products short name :
[b-Amyloid 1-40, 42]
products name syn :
[Anti -b-Amyloid 1-40, 42, CT]
clonality :
Monoclonal
isotype :
IgG1
clone :
[6D4]
host :
Mouse
reactivity :
Human
specificity :
Recognizes human C-terminal b-amyloid (aa1-40 and aa1-42). Crossreactivity: APP.
purity :
Purified. Purified by size exclusion chromatography. Grade: Highly Purified
form :
Supplied as a liquid in 2X PBS, 0.1% sodium azide, PEG, sucrose.
concentration :
0.1mg/ml
storage stability :
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
tested application :
ELISA (EL/EIA), Western Blot (WB), Immunocytochemistry (ICC). Other applications have not been tested.
app notes :
Suitable for use in ELISA, Immunocytochemistry and Western Blot. Dilution: ELISA: 0.05ug/ml. Western Blot: 1ug/ml for HRPO/ECL detection. Block with Casein/Tween 20 based blocking and blot incubation buffer. Immunocytochemistry: 0.1-1ug/ml
other info1 :
Immunogen: Synthetic peptide corresponding to aa1-40 and aa1-42 of C-terminal human b-amyloid, conjugated to KLH.
products categories :
Antibodies; Abs to Amyloid
products description :
The beta-amyloid peptide (beta A4), proteolytically released from the amyloid precursor protein (APP), is the principal component of senile plaques in Alzheimer's disease. Cleavage of APP by alpha-secretase or alternatively by beta-secretase leads to generation and extracellular release of soluble APP peptides, S-APP-alpha and S-APP-beta, respectively, and the retentionof corresponding membrane-anchored C-terminal fragments, C83 and C99. Subsequent processing of C83 by gamma-secretase yields P# peptides. This is the major secretory pathway and is nonamyloidogenic. Alternatively, presenilin/ nicastrin-mediated gamma-secretase processing of C99 releases the amyloid -beta 42 (Abeta42), major components of amyloid plaques, and the cytotoxic C-terminal fragments, gamma-CTF (50), gamma - CTF (57) and gamma-CTF (59).
size1 :
0.1 mg
price1 :
730 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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