antibody

HLA Class 1 Antigen Bw6,B77

MBS602966

0.1 mL

375 USD

monoclonal

mouse

nonconjugated

[4i122]

immunocytochemistry, flow cytometry, FACS

Antibody

HLA Class 1 Antigen Bw6,B77

[HLA Class 1 Antigen Bw6,B77]

[Anti -HLA Class 1 Antigen Bw6,B77]

Monoclonal

IgM

[4i122]

Mouse

Human

Recognizes human HLA Class 1 Antigen Bw6,B77.

Ascites

Supplied as a lyophilized powder in PBS, 1% BSA. Reconstitute to 100ul sterile ddH2O to make a 10X stock solution.

Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Flow Cytometry (FC/FACS), Immunofluorescence (IF)

Suitable for use in Flow Cytometry, Cell Typing, Tissue Staining, and Chimerism Studies. Dilution: Cytotoxicity: Add 0.9ml of 1% BSA in PBS to 100ul of 10X working dilution. This antibody has not been tested in methodologies other than Microcytotoxicity Test. Potential applications include Flow Cytometry, Cell Typing, Tissue Staining and Chimerism Studies.

Source: Ascites Fluid

Antibodies; Abs to HLA

The human leukocyte antigen system (HLA) is the name of the major histocompatibility complex (MHC) in humans. The superlocus contains a large number of genes related to immune system function in humans. This group of genes resides on chromosome 6, and encodes cell-surface antigen-presenting proteins and many other genes. The HLA genes are the human versions of the MHC genes that are found in most vertebrates (and thus are the most studied of the MHC genes). The proteins encoded by certain genes are also known as antigens, as a result of their historic discovery as factors in organ transplantations. The major HLA antigens are essential elements for immune function. Different classes have different functions: HLA class I antigens (A, B & C) present peptides from inside the cell (including viral peptides if present). These peptides are produced from digested proteins that are broken down in the proteasomes. The peptides are generally small polymers, about 9 amino acids in length. Foreign antigens attract killer T-cells (also called CD8 positive- or cytotoxic T-cells) that destroy cells.

0.1 mL

375 USD