catalog number :
MBS602670
products full name :
Endogenous Retrovirus Type K, Envelope Protein (HERV K)
products short name :
Endogenous Retrovirus Type K, Envelope Protein
products name syn :
Anti -Endogenous Retrovirus Type K, Envelope Protein (HERV K)
other names :
envelope protein
specificity :
Recognizes Endogenous Retrovirus Type K, Human, Envelope Protein (HERV K).
purity :
Affinity Purified. Purified by Protein G affinity chromatography.
form :
Supplied as a liquid in PBS, pH 7.4.
storage stability :
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
tested application :
ELISA (EL/EIA)
app notes :
Suitable for use in ELISA. Dilution: ELISA: 1:8000
other info1 :
Immunogen: HERV K envelope antigen (79.5kD)
products categories :
Antibodies; Abs to Infectious Disease
products description :
Endogenous retroviruses contribute to the evolution of the host genome and can be associated with diseases in their hosts. Human endogenous retrovirus K (HERV-K) is related to mouse mammary tumor virus (MMTV) and is present in the genomes of catarrhines (humans, apes, and cercopithecoids (old world monkeys)). All humans have about 30 to 50 HERV-K proviruses in their germline DNA. Expression of HERV-K genes has been reported in several tissues including male germ cell tumors and normal placenta where budding viral particles can be detected.
ncbi acc num :
AAD33055.1
uniprot summary :
ENK7: Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. This envelope protein has superantigenic properties. Belongs to the beta type-B retroviral envelope protein family. HERV class-II K(HML-2) env subfamily. Protein type: Membrane protein, integral. Chromosomal Location of Human Ortholog: 1q23.3