catalog number :
MBS601438
products full name :
Prostaglandin D Synthase, Hematopoietic form (PGD Synthase)
products short name :
Prostaglandin D Synthase, Hematopoietic form
products name syn :
Anti -Prostaglandin D Synthase, Hematopoietic form (PGD Synthase)
reactivity :
Human, Mouse
specificity :
Recognizes mouse H-PGDS. Species Crossreactivity: human.
purity :
Purified. Purified
form :
Supplied as a liquid in PBS, pH 7.2, 0.1% BSA, 0.02% sodium azide, 50% glycerol.
storage stability :
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
tested application :
Western Blot (WB), Immunohistochemistry (IHC)
app notes :
Suitable for use in Immunohistochemistry and Western Blot. Dilution: Immunohistochemistry: 1:1000-1:5000. Western Blot: 1:1000. Incubate for 1 hour at RT. Optimal dilution determined by the researcher.
other info1 :
Immunogen: Recombinant mouse hematopoietic prostaglandin D synthase (H-PGDS).
products categories :
Antibodies; Abs to Prostaglandins
products description :
Prostaglandin D synthase (PGD synthase) catalyzes the isomerization of PGH2 to produce PGD2. PGD2 induces sleep, regulates nociception, inhibits platelet aggregation, and acts as an allergic mediator. Two distinct types of PGD synthase have been identified, namely the lipocalin-type enzyme (-trace) and the hematopoietic enzyme. Lipocalin-type PGD synthase is localized in the central nervous system and male genital organs of various mammals and the human heart. This enzyme has been identified as beta-trace, which is a major protein in human cerebrospinal fluid. Hematopoietic PGD synthase is widely distributed in the peripheral tissues and is localized in the antigen-presenting cells, mast cells, and megakaryocytes. This enzyme, which requires glutathione for activity, belongs to the sigma-class of glutathione S-transferases and is approximately 23kD in size.