antibody

HIV-1 p66, Strain IIIB (Reverse Transcriptase, Human Immunodeficiency Virus-1)

MBS601420

0.1 mg

550 USD

monoclonal

mouse

nonconjugated

5i7

western blot, ELISA, immunohistochemistry, immunocytochemistry, neutralization, immunoprecipitation, enzyme immunoassay

Antibody

HIV-1 p66, Strain IIIB (Reverse Transcriptase, Human Immunodeficiency Virus-1)

HIV-1 p66, Strain IIIB

Anti -HIV-1 p66, Strain IIIB (Reverse Transcriptase, Human Immunodeficiency Virus-1)

Monoclonal

IgG

5i7

Mouse

Recognizes native and recombinant HIV-1 p66, Strain IIIB.

Highly Purified. Purified, 95%

Supplied as a liquid in PBS, pH 7.2. No stabilizers or preservatives added.

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

ELISA (EL/EIA), Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Neutralization

Suitable for use in ELISA, Western Blot, Neutralization, Immunoprecipitation, Immunocytochemistry and Immunohistochemistry. Dilution: ELISA: 10-100ng/ml. Western Blot: 1-5ug/ml. Neutralization: Neutralizes HIV-1 p66, Strain IIIB as determined by HIV-1 p66 assay in vitro.

Immunogen: Recombinant HIV-1 p66

Antibodies; Abs to Infectious Disease HIV

Human immunodeficiency virus (HIV) is a retrovirus that can lead to a condition in which the immune system begins to fail, leading to opportunistic infections. HIV primarily infects vital cells in the human immune system such as helper T cells (specifically CD4+ T cells), macrophages and dendritic cells. HIV infection leads to low levels of CD4+ T cells through three main mechanisms: primarily, direct viral killing of infected cells; secondly, increased rates of apoptosis in infected cells; and thirdly, killing of infected CD4+ T cells by CD8 cytotoxic lymphocytes that recognize infected cells. When CD4+ T cell numbers decline below a critical level, cell-mediated immunity is lost, and the body becomes progressively more susceptible to opportunistic infections. HIV was classified as a member of the genus Lentivirus, part of the family of Retroviridae. Lentiviruses have many common morphologies and biological properties. Many species are infected by lentiviruses, which are characteristically responsible for long-duration illnesses with a long incubation period. Lentiviruses are transmitted as single-stranded, positive-sense, enveloped RNA viruses. Upon entry of the target cell, the viral RNA genome is converted to double-stranded DNA by a virally encoded reverse transcriptase that is present in the virus particle.

0.1 mg

550 USD