catalog number :
MBS6013362
products full name :
CTAGE1 (Cutaneous T-cell Lymphoma-associated Antigen 1, Protein cTAGE-1, Cancer/Testis Antigen 21.1, CT21.1, CTAGE2, Cutaneous Lymphocyte Antigen, CLA)
products short name :
[CTAGE1]
products name syn :
[Anti -CTAGE1 (Cutaneous T-cell Lymphoma-associated Antigen 1, Protein cTAGE-1, Cancer/Testis Antigen 21.1, CT21.1, CTAGE2, Cutaneous Lymphocyte Antigen, CLA)]
other names :
[cTAGE family member 2 isoform 1; cTAGE family member 2; cTAGE family member 2; protein cTAGE-2; cancer/testis antigen 21.2; cancer/testis antigen family 21, member 1; cancer/testis antigen family 21, member 2; cutaneous T-cell lymphoma-associated antigen 2; cutaneous T-cell lymphoma-associated antigen 1; Cancer/testis antigen 21.2]
other gene names :
[CTAGE1; CTAGE1; CTAGE; CT21.1; CT21.2; CTAGE-1; CTAGE-2; CTAGE2; Protein cTAGE-2; CT21.2]
uniprot entry name :
CTGE2_HUMAN
reactivity :
Human, Mouse
specificity :
Recognizes human Cutaneous Lymphocyte Antigen. Species Crossreactivity: mouse.
form :
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
storage stability :
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
tested application :
Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
app notes :
Suitable for use in Flow Cytometry and Immunohistochemistry. Dilution: Flow Cytometry: 2ug/10e5 cells in 100ul. Immunohistochemistry: Acetone-fixed, frozen. Immunohistochemistry: Formalin fixed paraffin embedded
other info1 :
Immunogen: Human Cutaneous Lymphocyte Antigen.
products categories :
Antibodies; Abs to Proteins
products description :
Cutaneous Lymphocyte-assiciated Antigen (CLA) is a 140kD homodimer protein recognized by a unique monoclonal antibody. It is expressed on T lymphocytes in skin, subsets of peripheral blood memory T cells, NK cells, memory B cells and dendritic cells, as well as on monocytes, granulocytes and activated endothelial cells. CLA is a carbohydrate epitope of sialic acid- and fucose-modified P-selectin glycoprotein ligand-1 (PSGL-1), a surface glycoprotein expressed on majority of peripheral blood leukocytes. CLA is a subset ligand for E-selectin, P-selectin, and L-selectin. It plays a role in memory lymphocyte homing, tethering and rolling. Treatment of activated HUVEC cells with this antibody inhibits lymphocyte adhesion.
ncbi acc num :
NP_758441.2
ncbi gb acc num :
NM_172241.2
ncbi mol weight :
85,282 Da
uniprot summary :
cTAGE-2: Belongs to the cTAGE family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Cancer Testis Antigen (CTA); Membrane protein, multi-pass; Membrane protein, integral. Chromosomal Location of Human Ortholog: 18p11.2. Cellular Component: integral to membrane