catalog number :
MBS6011273
products full name :
Vaccinia Virus B5R (Smallpox, VACV, VV)
products short name :
[Vaccinia Virus B5R]
products name syn :
[Anti -Vaccinia Virus B5R (Smallpox, VACV, VV)]
specificity :
Recognizes variola virus Smallpox B5R.
form :
Supplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide.
concentration :
0.5 mg/ml
storage stability :
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
tested application :
Western Blot (WB)
app notes :
WB: 1-3ug/ml. Optimal dilutons to be determined by the researcher.
image1 heading :
Western Blot (WB)
other info1 :
Grade: Affinity Purified. Purity: Purified by Protein G affinity chromatography. Positive Control: A partial recombinant fusion protein. Immunogen: Synthetic peptide corresponding to a fragment of residues within the following region of aa33-62 of B5R protein. Species Sequence Homology: human, chimpanzee, canine, rat, mouse, chicken, zebrafish; 100%, Xenopus , 92%
products categories :
Antibodies; Abs to Infectious Disease
products description :
B5R, a 561aa membrane protein containing ankyrin repeats that mediate protein-protein interactions and is related to the regulators of complement activation (RCA) superfamily. It consists of four short consensus repeats (SCRs) and transmembrane anchor region or the CT (cytoplasmic tail). Its transmembrane domain is the major determinant for targeting the B5R protein to the outer membrane of EEV (extracellular enveloped virus) and for supporting EEV formation, thus playing an important role in the process of virus envelopment and release. It may also be involved in viral evasion from host immune responses. B5R is essential for efficient wrapping of IMV, actin tail formation, normal plaque size, virus virulence, incorporation of the protein into EEV and for EEV formation.