catalog number :
MBS6010296
products full name :
SYTL1, ID (SYTL1, SLP1, Synaptotagmin-like protein 1, Exophilin-7, Protein JFC1)
products short name :
SYTL1
products name syn :
Anti -SYTL1, ID (SYTL1, SLP1, Synaptotagmin-like protein 1, Exophilin-7, Protein JFC1)
other names :
SYTL1 protein, partial; Synaptotagmin-like protein 1; synaptotagmin-like protein 1; exophilin-7; NADPH oxidase-related, C2 domain-containing protein; synaptotagmin-like 1; Exophilin-7; Protein JFC1
other gene names :
SYTL1; SYTL1; JFC1; SLP1; SLP1
uniprot entry name :
SYTL1_HUMAN
specificity :
Recognizes human SYTL1.
purity :
Affinity Purified. Purified by Protein A affinity chromatography.
form :
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
concentration :
0.49mg/ml
storage stability :
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
tested application :
ELISA (EL/EIA), Western Blot (WB)
app notes :
Suitable for use in Western Blot. Dilution: Western Blot: 1:100-500. Optimal dilutions to be determined by the researcher.
other info1 :
Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 296-325 in the central region of human SYTL1, UnitProt Acession# Q8IYJ3
products categories :
Antibodies; Abs to Syntaxin, Synaptotagmin, Synaptophysin
products description :
SYTL1 may play a role in vesicle trafficking (By similarity). It binds phosphatidylinositol 3,4,5-triphosphate. Acts as a RAB27A effector protein and may play a role in cytotoxic granule exocytosis in lymphocytes (By similarity).
ncbi acc num :
AAH09224.2
ncbi pathways :
Deregulation Of Rab And Rab Effector Genes In Bladder Cancer Pathway (698757)
uniprot summary :
SYTL1: May play a role in vesicle trafficking. Binds phosphatidylinositol 3,4,5-trisphosphate. Acts as a RAB27A effector protein and may play a role in cytotoxic granule exocytosis in lymphocytes. 2 isoforms of the human protein are produced by alternative splicing. Chromosomal Location of Human Ortholog: 1p36.11. Cellular Component: extrinsic to plasma membrane; melanosome; plasma membrane. Molecular Function: protein binding; neurexin binding; Rab GTPase binding. Biological Process: intracellular protein transport; exocytosis