antibody

HIV-2 p24, Capsid Protein (Human Immunodeficiency Virus-2)

MBS600736

0.1 mg

665 USD

monoclonal

mouse

nonconjugated

8.F.156

western blot, immunocytochemistry, immunoprecipitation

Antibody

HIV-2 p24, Capsid Protein (Human Immunodeficiency Virus-2)

HIV-2 p24, Capsid Protein

Anti -HIV-2 p24, Capsid Protein (Human Immunodeficiency Virus-2)

Monoclonal

IgG1

8.F.156

Mouse

Recognizes p24 of HIV-1 and HIV-2. Reactive in IFA of infected cells, immunoprecipitation p24 protein from radiolabeled infected cell extracts.

Purified. Purified IgG

Supplied as a liquid in PBS, pH 7.4, 0.1% sodium azide.

May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Western Blot (WB), Immunoprecipitation (IP), Immunofluorescence (IF)

Suitable for use in Immunofluorescence, Immunoprecipitation and Western Blot.

Immunogen: Purified HIV-1 (Strain IIIB) lysate

Antibodies; Abs to Infectious Disease HIV

Capsid protein p24 forms the conical core of the virus that encapsulates the genomic RNA-nucleocapsid complex. Structural studies demonstrated two distinct domains (N and C-terminal domains) that have different roles in the virus morphogenesis. Additionally, the level of p24 found in the blood serum is used as an indicator of HIV progression. HIV-1 performs highly complex orchestrated tasks during the assembly, budding, maturation and infection stages of the viral replication cycle. During viral assembly, the proteins form membrane associations and self-associations that ultimately result in budding of an immature virion from the infected cell. Gag precursors also function during viral assembly to selectively bind and package two plus strands of genomic RNA.

0.1 mg

665 USD