antibody

PLIN2 (ADFP, Perilipin-2, Adipophilin, Adipose Differentiation-related Protein, ADRP)

MBS6005517

0.1 mg

515 USD

polyclonal

rabbit

nonconjugated

human, rat

Antibody

PLIN2 (ADFP, Perilipin-2, Adipophilin, Adipose Differentiation-related Protein, ADRP)

[PLIN2]

[Anti -PLIN2 (ADFP, Perilipin-2, Adipophilin, Adipose Differentiation-related Protein, ADRP)]

[perilipin-2; Perilipin-2; perilipin-2; adipophilin; adipose differentiation-related protein; perilipin 2; Adipophilin; Adipose differentiation-related protein]

[PLIN2; PLIN2; ADFP; ADRP; ADFP; ADRP]

PLIN2_HUMAN

Polyclonal

IgG

Rabbit

Human, Monkey, Mouse, Rat

Recognizes human ADFP at ~48kD. Species Crossreactivity: mouse, rat and monkey.

Affinity Purified. Purified by affinity chromatography.

Supplied as a liquid in PBS, 0.5% BSA, 0.01% thimerosal, 30% glycerol.

0.5 mg/ml

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

Suitable for use in Western Blot. Dilution: Western Blot: 0.5-4ug/ml

Western Blot (WB)

Immunogen: Synthetic peptide corresponding to aa426 from human ADFP.

Antibodies; Abs to Obesity Proteins

Adipocyte differentiation-related protein (ADFP) also called Adipophilin is associated with the globule surface membrane material. ADFP (Adipophilin) occurs in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells. ADFP may be a possible indicator for the identification of specialized differentiated cells containing lipid droplets and for diseases that link to fat-accumulating cells.

34577059

NP_001113.2

NM_001122.3

Q99541

48,075 Da

Adipogenesis Pathway (198832); Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway (160977); HIF-1-alpha Transcription Factor Network Pathway (138045); Metabolism Pathway (477135); Metabolism Of Lipids And Lipoproteins Pathway (160976); PPARA Activates Gene Expression Pathway (530749); Regulation Of Lipid Metabolism By Peroxisome Proliferator-activated Receptor Alpha (PPARalpha) Pathway (119544)

The protein encoded by this gene belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2011]

perilipin 2: May be involved in development and maintenance of adipose tissue. Belongs to the perilipin family. Protein type: Endoplasmic reticulum. Chromosomal Location of Human Ortholog: 9p22.1. Cellular Component: endoplasmic reticulum; plasma membrane; extracellular region; lipid particle; nucleus; cytosol. Biological Process: long-chain fatty acid transport; response to drug; sequestering of lipid; cellular lipid metabolic process; response to organic cyclic substance

0.1 mg

515 USD