catalog number :
MBS600536
products full name :
Tetrahydrocannabinol, D9 (THC)
products short name :
[Tetrahydrocannabinol, D9]
products name syn :
[Mouse anti-Tetrahydrocannabinol, D9 (THC)]
specificity :
Recognizes Tetrahydrocannabinol, D9
purity :
Purified by Protein A affinity chromatography. (>90% by SDS-PAGE).
form :
Supplied as a liquid in 10mM sodium phosphate pH 7.4, 150mM sodium chloride, 0.09% sodium azide
concentration :
5.65 mg/ml
storage stability :
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
tested application :
ELISA (EL/EIA). Other applications not tested
app notes :
Optimal dilutions to be determined by the researcher.
other info1 :
Immunogen: 11-Nor-delta 9-THC acid conjugated at the carboxyl group
other info2 :
Grade: Affinity Purified
products categories :
Antibodies; Abs to Drugs
products description :
Cannabinoids, a group of C21 compounds present in Cannabis sativa L., their carboxylic acids, analogs, and transformation products, are the active ingredients found in hasish and marihuana. (-)-trans-D9-tetrahydrocannabinol (D9-THC) is the major psychopharmacologically active component of cannabis. Cannabis affect cognition and memory, euphoria and sedation, and antinociception (analgesia) without the respiratory depression problems associated with opioid analgesics. D9-THC is also immunosuppressive and impairs cell-mediated immunity, humoral immunity and cellular defenses against a variety of infectious agents both in vivo and in vitro. To date, two sub-types of the G-protein coupled cannabinoid receptor, CB1 and CB2, have been identified. The first brain-derived endogenous cannabinoids, an unsaturated fatty-acid ethanolamide, arachidonylethanolamide (AEA, also called anandamide) was found in brain. AEA has higher affinity for the CB1 than for the CB2. THC is rapidly adsorbed by the lungs and almost completely metabolized. The major metabolite is 11-nor-delta-9-tetrahydrocannbinol-9-carboxylic acid and is found with other metabolites in plasma, feces, and urine. THC-metabolites can be detected within hours or exposure and may be detectable for several days. A cut-off level of 50ng/ml marijuana metabolites has been selected as the initial screening level by the US Dept. of Health.