CD44V7 (HCAM, Homing Cell Adhesion Molecule, Pgp-1, Phagocytic Glycoprotein-1, Hermes Antigen, Lymphocyte Homing Receptor, ECM-III, HUTCH-1) | MyBioSource MBS600463 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

CD44V7 (HCAM, Homing Cell Adhesion Molecule, Pgp-1, Phagocytic Glycoprotein-1, Hermes Antigen, Lymphocyte Homing Receptor, ECM-III, HUTCH-1)

catalog :

MBS600463

quantity :

0.1 mg

price :

530 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

[6D33]

reactivity :

human, mouse

application :

western blot, flow cytometry, FACS

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS600463

products type :

Antibody

products full name :

CD44V7 (HCAM, Homing Cell Adhesion Molecule, Pgp-1, Phagocytic Glycoprotein-1, Hermes Antigen, Lymphocyte Homing Receptor, ECM-III, HUTCH-1)

products short name :

[CD44V7]

products name syn :

[Anti -CD44V7 (HCAM, Homing Cell Adhesion Molecule, Pgp-1, Phagocytic Glycoprotein-1, Hermes Antigen, Lymphocyte Homing Receptor, ECM-III, HUTCH-1)]

other names :

[CD44 antigen; CD44 antigen; CD44 antigen; PGP-I; HUTCH-I; ECMR-III; hermes antigen; hyaluronate receptor; lymphocyte antigen 24; phagocytic glycoprotein 1; phagocytic glycoprotein I; extracellular matrix receptor III; GP90 lymphocyte homing/adhesion receptor; CD44 antigen; Extracellular matrix receptor III; ECMR-III; GP90 lymphocyte homing/adhesion receptor; HUTCH-I; Hermes antigen; Hyaluronate receptor; Lymphocyte antigen 24; Ly-24; Phagocytic glycoprotein 1; PGP-1; Phagocytic glycoprotein I]

other gene names :

[Cd44; Cd44; Ly-24; Pgp-1; HERMES; AU023126; AW121933; AW146109; Ly-24; ECMR-III; Ly-24; PGP-1; PGP-I]

uniprot entry name :

CD44_MOUSE

clonality :

Monoclonal

isotype :

IgG1

clone :

[6D33]

host :

Mouse

reactivity :

Human

specificity :

Recognizes an epitope encoded by exon v7 on the variant portion of human CD44.

purity :

Purified. Purified.>95% (SDS-PAGE)

form :

Supplied as a liquid in PBS, pH 7.3

concentration :

1mg/ml

storage stability :

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

tested application :

Western Blot (WB), Flow Cytometry (FC/FACS)

app notes :

Suitable for use in Flow Cytometry and Western Blot. Not suitable for use in Immunohistochemistry.,. Dilution: Flow Cytometry: 1:20

products categories :

Antibodies; Abs to CD Markers

ncbi gi num :

30316353

ncbi acc num :

P15379.3

uniprot acc num :

P15379

ncbi mol weight :

85,617 Da

ncbi pathways :

Cytokine Signaling In Immune System Pathway (819682); Disease Pathway (819462); ECM-receptor Interaction Pathway (83265); ECM-receptor Interaction Pathway (479); Epstein-Barr Virus Infection Pathway (585576); Epstein-Barr Virus Infection Pathway (587115); Extracellular Matrix Organization Pathway (819039); Glycosaminoglycan Metabolism Pathway (819212); Hematopoietic Cell Lineage Pathway (83275); Hematopoietic Cell Lineage Pathway (489)

uniprot summary :

CD44: Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events. Interacts with PKN2. Interacts with HA, as well as other glycosaminoglycans, collagen, laminin, and fibronectin via its N-terminal segment. Interacts with ANK, the ERM proteins (VIL2, RDX and MSN), and NF2 via its C-terminal segment. Isoform 10 (epithelial isoform) is expressed by cells of epithelium and highly expressed by carcinomas. Expression is repressed in neuroblastoma cells. 19 isoforms of the human protein are produced by alternative splicing. Protein type: Motility/polarity/chemotaxis; Receptor, misc.; Membrane protein, integral; Cell adhesion. Cellular Component: Golgi apparatus; protein complex; cell surface; focal adhesion; membrane; basolateral plasma membrane; cytoplasm; apical plasma membrane; integral to membrane; plasma membrane; nucleus; external side of plasma membrane. Molecular Function: hematopoietin/interferon-class (D200-domain) cytokine receptor activity; protein binding; cytokine binding; hyaluronic acid binding; phosphoprotein binding; protein kinase binding; epidermal growth factor receptor binding; hyalurononglucosaminidase activity. Biological Process: cell migration; positive regulation of heterotypic cell-cell adhesion; Wnt receptor signaling pathway; positive regulation of neutrophil apoptosis; negative regulation of caspase activity; positive regulation of peptidyl-serine phosphorylation; hyaluronan catabolic process; negative regulation of DNA damage response, signal transduction by p53 class mediator; positive regulation of peptidyl-tyrosine phosphorylation; negative regulation of mature B cell apoptosis; ureteric bud branching; regulation of cell growth; cell adhesion; healing during inflammatory response; neurite development; positive regulation of adaptive immune response; negative regulation of apoptosis

size1 :

0.1 mg

price1 :

530 USD

more info or order :

MyBioSource product webpage