catalog number :
MBS6004097
products full name :
GNRH2, ID (GNRH2, Progonadoliberin-2, Progonadoliberin II, Gonadoliberin-2, Gonadoliberin II, Gonadotropin-releasing hormone II, Luliberin II, Luteinizing hormone-releasing hormone II, GnRH-associated peptide 2, GnRH-associated peptide II)
products short name :
[GNRH2]
products name syn :
[Anti -GNRH2, ID (GNRH2, Progonadoliberin-2, Progonadoliberin II, Gonadoliberin-2, Gonadoliberin II, Gonadotropin-releasing hormone II, Luliberin II, Luteinizing hormone-releasing hormone II, GnRH-associated peptide 2, GnRH-associated peptide II)]
other names :
[GNRH2 protein; Progonadoliberin-2; progonadoliberin-2; luliberin II; progonadoliberin II; luteinizing hormone-releasing hormone II; gonadotropin-releasing hormone 2; Progonadoliberin IICleaved into the following 2 chains:Gonadoliberin-2; Alternative name(s):; Gonadoliberin II; Gonadotropin-releasing hormone II; GnRH II; Luliberin II; Luteinizing hormone-releasing hormone II; LH-RH IIGnRH-associated peptide 2; Alternative name(s):; GnRH-associated peptide II]
other gene names :
[GNRH2; GNRH2; GnRH-II; LH-RHII; GnRH II; LH-RH II]
uniprot entry name :
GON2_HUMAN
specificity :
Recognizes Human GNRH2
purity :
Affinity Purified. Purified by Protein A affinity chromatography.
form :
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
concentration :
0.5 mg/ml
storage stability :
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
tested application :
ELISA (EL/EIA), Western Blot (WB), Flow Cytometry (FC/FACS)
app notes :
Suitable for use in Western Blot, Flow Cytometry. Dilution: . Western Blot: 1:1000. Flow Cytometry: 1:10-50. Optional dilutons to be determined by the researcher.
image1 heading :
Western Blot (WB)
image2 heading :
Flow Cytometry (FC/FACS)
other info1 :
Immunogen: GNRH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 32~62 amino acids from the Central region of human GNRH2, conjugated to KLH. Cellular location: secreted. Tissue location: midbrain; expressed at siganifigantly higher levels outside of the brain, particular kidney, bone marrow and prostate.
products categories :
Antibodies; Abs to Hormones, Steroids
products description :
The protein encoded by this gene is a preproprotein that is cleaved to form a secreted 10 aa peptide hormone. The secreted decapeptide regulates reproduction in females by stimulating the secretion of both luteinizing- and follicle-stimulating hormones.
ncbi acc num :
AAI15401.1
ncbi mol weight :
12,918 Da
ncbi pathways :
Class A/1 (Rhodopsin-like Receptors) Pathway (106357); G Alpha (q) Signalling Events Pathway (106043); GPCR Downstream Signaling Pathway (119548); GPCR Ligand Binding Pathway (161020); Gastrin-CREB Signalling Pathway Via PKC And MAPK (645295); GnRH Signaling Pathway (83091); GnRH Signaling Pathway (502); Hormone Ligand-binding Receptors Pathway (106369); Signal Transduction Pathway (477114); Signaling By GPCR Pathway (106356)
ncbi summary :
The protein encoded by this gene is a preproprotein that is cleaved to form a secreted 10 aa peptide hormone. The secreted decapeptide regulates reproduction in females by stimulating the secretion of both luteinizing- and follicle-stimulating hormones. Three transcript variants that encode unique proproteins but the same peptide hormone have been found for this gene. [provided by RefSeq, Jul 2008]
uniprot summary :
GNRH2: Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones. Belongs to the GnRH family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 20p13. Cellular Component: extracellular region. Molecular Function: hormone activity. Biological Process: multicellular organismal development; signal transduction