product summary
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company name :
MyBioSource
product type :
antibody
product name :
b2-Microglobulin (B2M)
catalog :
MBS600300
quantity :
0.2 mg
price :
780 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
[1.B.749]
reactivity :
human
application :
immunohistochemistry, immunocytochemistry, flow cytometry, FACS
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS600300
products type :
Antibody
products full name :
b2-Microglobulin (B2M)
products short name :
[b2-Microglobulin]
products name syn :
[Anti -b2-Microglobulin (B2M)]
other names :
[b2 microglobulin; HLA-G protein; HLA class I histocompatibility antigen, alpha chain G; HLA G antigen; b2 microglobulin; OTTHUMP00000029218; OTTHUMP00000029220; OTTHUMP00000033527; OTTHUMP00000159507; HLA class I molecule; MHC class I antigen G; HLA-G histocompatibility antigen, class I, G; major histocompatibility complex, class I, G]
other gene names :
[HLA-G; HLA-G; MHC-G]
uniprot entry name :
O02923_HUMAN
clonality :
Monoclonal
isotype :
IgG2a
clone :
[1.B.749]
host :
Mouse
specificity :
Recognizes human Beta 2-microglobulin (MW 12kDa). Does not react with Beta 2-microglobulin from other species. Recognizes the HLA-Beta 2-microglobulin complex, free or associated with the membrane. The exact epitope for the antibody has not been mapped
purity :
Purified
form :
Supplied as a lyophilized powder from PBS, 1mg/ml BSA. Reconstitute with 1ml sterile ddH2O.
concentration :
~0.2mg/ml (after reconstitution)
storage stability :
Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
tested application :
Immunohistochemistry (IHC), Flow Cytometry (FC/FACS), Immunofluorescence (IF)
app notes :
Immunofluorescence/Flow Cytometry: 10ul/5x10e5 cells/test. Immunohistochemistry: frozen sections of cell smears): 1:25-1:50. Optimal dilutions to be determined by the researcher.
other info1 :
Immunogen: Purified human Beta 2-microglobulin
other info2 :
Hybridoma: NS1/Ag4.1 myeloma cells with spleen cells of Balb/c mice. Grade: Purified
products categories :
Antibodies; Abs to Serum Proteins
products description :
b2-microglobulin non-covalently associates with the 44kD a-chain to form the HLA Class I antigen complex. Human b2-microglobulin associated with HLA Class I antigens is expressed on many types of cells including lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells, and epithelial cells. It is absent on erythrocytes.
ncbi gi num :
188468
uniprot acc num :
O02923
ncbi pathways :
Adaptive Immunity Signaling Pathway (366160); Allograft Rejection Pathway (83123); Allograft Rejection Pathway (535); Antigen Presentation: Folding, Assembly And Peptide Loading Of Class I MHC Pathway (366163); Antigen Processing And Presentation Pathway (83074); Antigen Processing And Presentation Pathway (485); Autoimmune Thyroid Disease Pathway (83121); Autoimmune Thyroid Disease Pathway (533); Cell Adhesion Molecules (CAMs) Pathway (83069); Cell Adhesion Molecules (CAMs) Pathway (480)
ncbi summary :
HLA-G belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-G is expressed on fetal derived placental cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exon 6 encodes the cytoplasmic tail. [provided by RefSeq]
uniprot summary :
Sequence similarities: Belongs to the MHC class I family. RuleBase RU004439
size1 :
0.2 mg
price1 :
780 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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