catalog number :
MBS6002643
products full name :
ProCollagen Type I Propeptide, CT (PICP)
products short name :
ProCollagen Type I Propeptide
products name syn :
Anti -ProCollagen Type I Propeptide, CT (PICP)
other names :
Procollagen C-endopeptidase enhancer 1; Procollagen C-endopeptidase enhancer 1; procollagen C-endopeptidase enhancer 1; astroglial cell transcript 2; procollagen C-proteinase enhancer 1; procollagen C-proteinase enhancer protein; procollagen COOH-terminal proteinase enhancer 1; type 1 procollagen C-proteinase enhancer protein; type I procollagen COOH-terminal proteinase enhancer; procollagen C-endopeptidase enhancer protein; P14; Procollagen COOH-terminal proteinase enhancer 1; PCPE-1; Procollagen C-proteinase enhancer 1; Type 1 procollagen C-proteinase enhancer protein; Type I procollagen COOH-terminal proteinase enhancer
other gene names :
Pcolce; Pcolce; P14; Astt2; Astt-2; PCPE-1; Pcpe1; PCPE-1
uniprot entry name :
PCOC1_MOUSE
specificity :
Recognizes native human ProCollagen Type I Propeptide (PICP).
purity :
Affinity Purified. Purified by Protein A affinity chromatography.
form :
Supplied as a liquid in PBS, pH 7.4, 15mM sodium azide.
concentration :
1.03mg/ml
storage stability :
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
tested application :
ELISA (EL/EIA), Immnuoprecipitation (IP), Western Blot (WB). Other applications not tested.
app notes :
Suitable for use in ELISA, Immunoprecipitation and Western Blot. Optimal dilutions to be determined by the researcher. Recommended Pair:. Capture: MBS642106. Detection: MBS6002643
other info1 :
Immunogen: PICP purified from second trimester amniotic fluid. Culture Medium: Hybridoma Serum Free Medium
other info2 :
Hybridoma: X63-Ag8.653 myeloma cells with spleen cells from Balb/c mice.
products categories :
Antibodies; Abs to Collagen
products description :
Type I collagen is present in connective tissue and bone where it makes up about 90% of the organic matrix. Type I collagen is produced from type-I procollagen by the proteolytic cleavage of N- and C-telopeptides, which are released into the circulation. The propeptides can be measured in serum as markers of the production of trype-I collagen. Elevated values of these propeptides are found in serum from patients with various metabolic or malignant bone diseases. Procollagen type I C-terminal propeptide (PICP) has a molecular mass of ~100kD. Its normal concentration in serum depends on age and sex.
ncbi mol weight :
50,168 Da
ncbi pathways :
Collagen Biosynthesis And Modifying Enzymes Pathway (819041); Collagen Formation Pathway (819040); Extracellular Matrix Organization Pathway (819039); MRNA Processing Pathway (198369)
uniprot summary :
PCOLCE: Binds to the C-terminal propeptide of type I procollagen and enhances procollagen C-proteinase activity. Protein type: Secreted, signal peptide; Secreted; Extracellular matrix. Cellular Component: extracellular matrix; extracellular space; extracellular region. Molecular Function: heparin binding; collagen binding; protease activator activity. Biological Process: proteolysis