protein

Middle East SARS spike protein S1

MBS596077

1 mg

315 USD

Recombinant Protein

Middle East SARS spike protein S1

[Middle East SARS spike S1]

[MERS-CoV S1 spike protein]

E. coli

>95% pure (12% SDS-PAGE, Coomassie blue strain). Proprietary chromatographic technique

Purified, Liquid

1.4 mg/mL

Upon receipt, store at -20°C. Avoid multiple freeze/thaw cycles.

Immunoassay (IA)

SDS-PAGE

Buffer: PBS with 25mM arginin. Preservative: 0.05% sodium azide

Note: Centrifuge before opening to ensure complete recovery of vial contents.

Since April 2012. cases of the Middle East Respiratory Syndrome Coronavirus (MERS-CoV) have been identified in middle east and other clJulltries. This virus is also classified into coronaviruse family, causing severe illnesses with over 40% mortality. Like other coronaviruses, large surface spike glycoprotein is one important structural protein of this virus, it is located over the virion surface to bind to and entry into the target cell. Sipke protein has two domains, S1 and S2. S 1 domain is responsible for cellular tropism and interaction with target cell, while S2 domain responsible for membrane fusion. C tenninus of S 1 contains a receptor binding domain with potential for vaccine development and diagnosis.A peptide from amino acids 56 to 295 of spike protein S 1 is expressed and puritied from L coli. a 6 x His tag is attached to its C terminus .

Joural of virology, 2013, 87: 9939-9942

1 mg

315 USD

2 mg

545

5 mg

1220