catalog number :
MBS592417
products full name :
mAb anti-Amyloid Beta Peptide 40
products short name :
[Beta amyloid peptide]
products gene name :
[Ab40]
reactivity :
Human, Mouse, Rat
specificity :
This antibody recognizes the C-terminal sequence (GLMVGGVV) of Abeta40 and full length Abeta40, but does not react with Nterminal peptide (DAEFRHDS), or full length human Abeta42 and Abeta43.
purity :
Protein G Affinity Purified
form :
Lyophilized from a solution in 0.01M PBS pH7.2
storage stability :
Store at -20°C
tested application :
Immunohistochemistry (IHC)
image1 heading :
Immunohistochemistry (IHC)
other info1 :
Research Area: Aging and Neurodegenerative Diseases. Fusion Myeloma: Sp2/0-Ag14
other info2 :
Immunogen: Full length Abeta40. Target Protein: Amyloid beta peptide 40. Reconstitution: Double distilled water is recommended to adjust the final concentration to 1.00 mg/ml.
products categories :
Monoclonal Antibodies to Neurological Disorder Proteins
products description :
Description: Mouse monoclonal antibody to C-terminal of amyloid beta peptide 40 (Abeta40). Background: Abeta40 and Abeta42 are the two major amyloid peptides formed after cleavage of amyloid precursor protein. In blood and cerebrospinal fluid, the concentration of Abeta40 is about 10 timers higher than that of Abeta42. Abeta40 is the main component in the amyloid deposit of vascular amyloid angiopathy. Detection of Abeta40 is useful for the predication of Alzheimer's disease. Lower than normal Abeta42/Abeta40 ratio in cerebrospinal fluid was found to be associated with increased risk of mild cognitive impairment and Alzheimer's disease.