catalog number :
MBS592410
products full name :
Rabbit Anti-Human Amyloid Beta Peptide 42 Polyclonal Antibody Datasheet.
products short name :
[Amyloid Beta peptide 42]
products gene name :
[Ab42]
reactivity :
Human, others not tested.
specificity :
This antibody recognizes human Abeta 42
purity :
Protein G Affinity Purified
form :
Lyophilized from a solution in 0.01M PBS, pH 7.2
storage stability :
Store at -20°C
tested application :
ELISA (EIA)
app notes :
Indirect ELISA: The antibody is reactive to full-length human Abeta42 in indirect ELISA. It has not been evaluated in sandwich ELISA assay.
other info1 :
Research Area: Alzheimer's Disease and Other Neurodegenerative Disease. Product Type: Primary antibody. Reconstitution: Double distilled water is recommended to adjust the final concentration to 1mg/ml.
other info2 :
Immunogen: Synthetic full-length human amyloid beta peptide 42 (Abeta42). Target Protein: Human Amyloid beta peptide 42
products categories :
Polyclonal Antibodies to Neurological Disorder Proteins
products description :
Description: Rabbit anti-human Amyloid beta peptide 42 polyclonal antibody. Background: Amyloid beta peptide 42 (Ab42) is best known for its role in the formation of senile plaques in the brain of patients with Alzheimer's disease. Ab42 and Ab40 are the two major amyloid peptides that are produced after cleavage of amyloid precursor protein by secretases. Ab42 (42 amino acids) is very fibrillogenic. The beta pleated structure of Ab42 constituents the initial and key component of the insoluble amyloid fibril in senile plaque. It is widely accepted that Ab42 contributes to the pathogenesis of Alzheimer's disease. One proposition is that the deposition of amyloid fibril onto the brain tissue results in Alzheimer's disease. Another is that the neurotoxicity of Ab42 oligomer is the cause of the disease.