catalog number :
MBS592331
products full name :
Transient Receptor Potential Cation Channel V1 (TRPV1)
products short name :
Transient Receptor Potential Cation Channel V1
products name syn :
Rabbit anti-Mouse transient receptor potential cation channel V1 (TRPV1) polyclonal antibody
other names :
transient receptor potential cation channel subfamily V member 1; Transient receptor potential cation channel subfamily V member 1; transient receptor potential cation channel subfamily V member 1; capsaicin receptor; osm-9-like TRP channel 1; transient receptor potential cation channel V1; vanilloid receptor 1; vanilloid receptor subtype 1; transient receptor potential cation channel, subfamily V, member 1; Osm-9-like TRP channel 1; OTRPC1; Vanilloid receptor 1
products gene name :
TRPV1
other gene names :
Trpv1; Trpv1; Vr1; VR-1; OTRPC1; TRPV1beta; TRPV1alpha
uniprot entry name :
TRPV1_MOUSE
reactivity :
Mouse, Other species with consensus TRPV1 sequence (GEKPPRLYDRR)
specificity :
This antibody is reactive to the 95kDa TRPV1 in mouse brain tissue extract on Western blot. Transient Receptor Potential Cation Channel V1 (TRPV1)
purity :
Protein G affinity purified
form :
Lyophilized in pH 7.4, 0.01M PBS.
storage stability :
Store at -20 degree C
tested application :
ELISA (EIA), Western Blot (WB)
app notes :
ELISA: Dilute the antibody approx. 1:100,000 for detection of Kchip1 peptide (QTKQRRPSKDK) coated on ELISA plate. Western blot: Dilute approx. 1:5,000 for Western blotting to detect the 95kDa TRPV1 in mouse brain tissue extract.
other info1 :
Target Protein: Transient receptor potential cation channel V1 (TRPV1). Immunogen: A synthetic peptide (GEKPPRLYDRR) corresponding to the amino acid sequence 105-115 of mouse TRPV1, conjugated with KLH for immunization. Reconstitution: Double distilled water is recommended to adjust the final concentration to 1.00mg/mL.
other info2 :
Research Area: Life science research, stem cell factor signalling, cancer research
products categories :
Primary antibodies; Polyclonal Antibodies to Signal Transduction
products description :
Rabbit anti-mouse transient receptor potential cation channel V1 (TRPV1) polyclonal antibody.
ncbi acc num :
NP_001001445.1
ncbi gb acc num :
NM_001001445.2
ncbi mol weight :
93,941 Da
ncbi pathways :
Inflammatory Mediator Regulation Of TRP Channels Pathway (948285); Inflammatory Mediator Regulation Of TRP Channels Pathway (948307); Ion Channel Transport Pathway (1111313); Neuroactive Ligand-receptor Interaction Pathway (83250); Neuroactive Ligand-receptor Interaction Pathway (462); Serotonin And Anxiety Pathway (672436); Stimuli-sensing Channels Pathway (1111316); TRP Channels Pathway (1111317); Transmembrane Transport Of Small Molecules Pathway (1111269)
uniprot summary :
TRPV1: a receptor for capsaicin and a non-selective cation channel that is structurally related to members of the TRP family of ion channels. Activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo. Protein type: Membrane protein, integral; Membrane protein, multi-pass; Receptor, misc.; Channel, cation. Cellular Component: postsynaptic membrane; neuron projection; cell projection; cell soma; membrane; dendrite; integral to membrane; plasma membrane; synapse; cytosol; cell junction; intrinsic to plasma membrane; external side of plasma membrane. Molecular Function: identical protein binding; excitatory extracellular ligand-gated ion channel activity; calcium channel activity; nucleotide binding; ion channel activity; phosphoprotein binding; ligand-gated ion channel activity; calmodulin binding; chloride channel regulator activity; transmembrane receptor activity; cation transmembrane transporter activity; calcium-release channel activity; cation channel activity; ATP binding. Biological Process: urinary bladder smooth muscle contraction; diet induced thermogenesis; catagen; positive regulation of nitric oxide biosynthetic process; positive regulation of apoptosis; microglial cell activation; response to pain; sensory perception of mechanical stimulus; thermoception; thermoregulation; sensory perception of pain; signal transduction; fever; behavioral response to pain; elevation of cytosolic calcium ion concentration; transport; calcium ion transport; transmembrane transport; cation transport; peptide secretion; detection of chemical stimulus involved in sensory perception of pain; response to organic nitrogen; glutamate secretion; smooth muscle contraction involved in micturition; response to heat; ion transport; lipid metabolic process; response to pH