catalog number :
MBS592257
products full name :
HRP conjugated mAb anti-human TSH
products short name :
TSH
products name syn :
Thyroid Stimulating Hormone (TSH), anti-human (*HRP Labeled); Horseradish peroxidase (HRP) conjugated mouse anti-Human thyroid stimulate Hormone (TSH) monoclonal antibody.
other names :
Tsh; Temperature-sensitive hemagglutinin tsh autotransporter; Autotransporter tsh
uniprot entry name :
TSH_ECOLX
reactivity :
Human. Others not tested
specificity :
Recombinant and natural human Thyroid Stimulating Hormone (TSH), anti-human (*HRP Labeled) beta subunit
purity :
Protein G affinity purified
form :
Mixture of 50% glycerol and 50% PH 7.2 0.01M PBS. Final PH = 7.0 +/- 0.1.
storage stability :
Store at -20 degree C
tested application :
ELISA: In combination with TSH capture antibody, TSH-1, this HRP conjugated antibody can be used as tracer antibody in sandwich ELISA for human TSH detection.
app notes :
Working Conditions: 1:1000-2000
other info1 :
Immunogen: Recombinant human TSH. Myeloma: Sp2/0-Ag14. Light Chain: Kappa. Target Protein: Human TSH. Fusion Myeloma: Not Known
other info2 :
Research Area: Hormone, metabolism. Intended Uses: Tracer*
products categories :
Tracer antibody in matched antibody pair, HRP conjugated.; Matched Antibody Pairs to Human Hormones
products description :
Thyroid stimulating hormone is secreted by pituitary gland in response to the stimulation of Thyrotropin Releasing Hormone (TRH) produced by hypothalamus. TSH binds to the TSH receptors on the surface of the follicular
cells in thyroid and stimulates theproduction of thyroid hormones (T4 and 13). TSH,13 and T4 play an important role in normal growth, brain development in young children, and regulate the metabolism in adults. TSH secretion is increased when T3 and T4 are insufficient. Elevated TSH, but low 13 and T4 levels indicate that thyroid cannot produce thyroid hormones at a normal rate and the condition is called hypothyroidism. IfT3 and T4 levels are high when TSH is at a low level, it indicates that thyroid is producing abnormally large amount thyroid hormones, and the condition is called hyperthyroidism which is manifested by hypermetabolic symptoms. TSH has an a subunit that is identical to the one in other glycoprotein hormones such as LH, FSH and HCG.
ncbi acc num :
AAA24698.1